Capital University of Physical Education and Sports
Beijing, Beijing Municipality, 100191, China
Completed
NCT Number: NCT06824571
Effects of Taurine Supplementation on Repetitive Sprint Performance and Exhaustion Time in College Students Under High-Temperature and High-Humidity Conditions
This study is designed to evaluate the effects of acute pre-exercise taurine supplementation at different doses on the performance of college students during exhaustive exercise and subsequent repetitive sprint (RS) activities in a high-temperature, high-humidity environment. Sixteen college students (8 male, 8 female) will participate in a single-blind, randomized, crossover-controlled trial. Participants will be divided into four groups: high-dose taurine (6g), medium-dose taurine (4g), low-dose taurine (1g), and placebo. Key performance metrics such as peak power (PP), mean power (MP), fatigue index (FI), exhaustion time (ET), reverse vertical jump height, heart rate (HR), blood lactate (BLA), and ratings of perceived exertion (RPE) will be measured.
The objective of this study is to assess how taurine supplementation influences exercise performance under these challenging environmental conditions. This study will help to better understand taurine's potential effects on exercise performance and contribute to nutritional strategies for athletes exposed to extreme conditions.
Completed
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Notify MeKey information
Conditions
Age range
20 day–26 day
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
About this study
This study is designed to evaluate the effects of taurine supplementation on exercise performance under extreme environmental conditions of high temperature and high humidity. The primary goal is to investigate whether taurine supplementation can enhance performance during exhaustive exercise and subsequent repetitive sprints (RS). Sixteen college students (8 male, 8 female) will participate in a single-blind, randomized, crossover-controlled trial. Participants will be divided into four groups receiving either high-dose (6g), medium-dose (4g), low-dose (1g) taurine supplementation, or placebo.
The study will involve a protocol with exhaustive exercise followed by six repetitive sprints. Performance metrics such as peak power (PP), mean power (MP), and fatigue index (FI) will be recorded. Additionally, physiological parameters, including heart rate (HR) and blood lactate (BLA), as well as subjective measures like ratings of perceived exertion (RPE), will be monitored. A standardized measurement protocol will be used to ensure consistency and accuracy across trials.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- School students
- Aged between 18 and 28 years
- No exercise-related risk, as indicated by a "no" response to all questions in the Physical Activity Readiness Questionnaire (PAR-Q)
- No taurine-based supplements consumed in the last month.
Exclusion criteria
- Individuals who do not meet the inclusion criteria
- Individuals with a history of cardiovascular issues, respiratory problems, or any condition that may impair exercise performance
- Participants who did not provide a "no" response to all questions in the Physical Activity Readiness Questionnaire (PAR-Q)
- Participants who consumed taurine-based supplements in the month preceding the study.
Treatment and study plan
High-Dose Taurine Supplementation (6g)
Dietary SupplementParticipants will receive taurine supplementation at a high dose of 6g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of high-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.
Medium-Dose Taurine Supplementation (4g)
Dietary SupplementParticipants will receive taurine supplementation at a medium dose of 4g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of medium-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.
Low-Dose Taurine Supplementation (1g)
Dietary SupplementParticipants will receive taurine supplementation at a low dose of 1g. The taurine will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention is designed to evaluate the effects of low-dose taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.
Placebo (0g Taurine)
Dietary SupplementParticipants will receive a placebo, consisting of an inactive substance (0g taurine). The placebo will be provided in powder form, dissolved in water, and administered 30 minutes prior to exercise. This intervention serves as a control arm to evaluate the effects of taurine supplementation on exercise performance, fatigue resistance, and recovery under high-temperature and high-humidity conditions.
Primary outcomes
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Change from Baseline in Peak Power (Watts)
Time frame: Measured at the end of each sprint on Day 1 and Day 7.
Description: Maximum power output during each of the 6 sprints, measured using a cycle ergometer.
Method of Assessment: Power output will be recorded for each sprint, and the peak value will be identified.
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Change from Baseline in Mean Power (Watts)
Time frame: Measured after all 6 sprints on Day 1 and Day 7.
Description: Average power output across all 6 sprints, reflecting sustained anaerobic performance.
Method of Assessment: Power output will be averaged across all sprints.
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Change from Baseline in Fatigue Index (%/s)
Time frame: Measured across all 6 sprints on Day 1 and Day 7.
Description: Rate of decline in power output across the sprints, representing fatigue resistance.
Method of Assessment: The decline in power output will be calculated as the difference between the first and last sprint, divided by the time interval.
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Change from Baseline in Exhaustion Time (seconds or minutes)
Time frame: Measured at the point of exhaustion during exhaustive exercise on Day 1 and Day 7.
Description: The duration participants can sustain exercise before reaching volitional exhaustion.
Method of Assessment: Time will be recorded from the start of exercise until the participant reaches exhaustion.
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Change from Baseline in Blood Lactate Levels (mmol/L)
Time frame: Measured at baseline (pre-exercise), immediately after exercise, and at specific recovery intervals on Day 1 and Day 7.
Description: Blood lactate levels will be measured to evaluate metabolic stress and recovery during exercise.
Method of Assessment: Blood samples will be collected at designated time points during recovery to assess lactate accumulation and clearance.
Secondary outcomes
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Change from Baseline in Ratings of Perceived Exertion (RPE)
Time frame: Measured continuously during exhaustive exercise and repetitive sprint activity on Day 1 and Day 7.
Description: Participants' perceived physical and mental exertion will be assessed using the Borg Rating of Perceived Exertion Scale.
Method of Assessment: Participants will rate their exertion on a scale from 6 (no exertion at all) to 20 (maximal exertion).
Sponsors and collaborators
Lead sponsor
Xiaodong Cheng
Other
Registry information
Acronym: TSPR
Important dates
- Study start
- 2024
- Primary completion
- 2025
- Study completion
- 2025
- First posted
- Feb 13, 2025
- Registry last updated
- Feb 13, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.