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Completed

NCT Number: NCT01907997

Effects of Systemic Lidocaine on Postoperative Quality of Recovery After Robot-assisted Thyroidectomy

Systemic lidocaine infusion may improve the patients' recovery quality and chronic post surgical pain after robot-assisted thyroidectomy

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Key information

Conditions

Thyroid Cancer Endocrine Gland Neoplasms Endocrine System Diseases Head and Neck Neoplasms Neoplasms Neoplasms by Site Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms Thyroid Diseases Thyroid Neoplasms

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei universiy college of medicine

Seoul, 120-752, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 20-65
  • ASA class I and II
  • Thyroid cancer patients who are scheduled for elective robot-assisted thyroidectomy

Exclusion criteria

  • Allergy to local anesthetics or contraindication to use of lidocaine
  • Pregnancy
  • Severe cardiovascular disease
  • Renal failure
  • Liver failure
  • Neurologic and psychologic disease
  • Chronic treatment with analgesics

Treatment and study plan

Systemic intravenous lidocaine infusion

Drug

In group L, intravenous lidocaine infusion(0.1mg/kg) for 10minutes after induction of anesthesia. After 10 minutes, lidocaine infusion continued at rate of 3mg/kg/hr during operation, and discontinued before move the patients to PACU.

Normal saline infusion

Drug

In group C, the patients receive same volume of normal saline

Primary outcomes

  1. Quality of recovery 40(QoR-40) score

    Time frame: 24hours after operation day

    Assessing change of the Quality of recovery 40(QoR-40) score between 24hours before and after operation

Secondary outcomes

  1. Assessing the presence of chronic postsurgical pain(CPSP)

    Time frame: 24hours after operation day

  2. aspect and site of CPSP

    Time frame: 24hours after operation day

Sponsors and collaborators

Lead sponsor

Yonsei University

Other

Registry information

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Jul 25, 2013
Registry last updated
Jun 9, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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