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Completed

NCT Number: NCT04913857

Effects of SUDOKU Mind Activation & Revitalizing Training on Cognitive Function in People With Mild Cognitive Impairment

This study aims to implement a SUDOKU Mind Activation and Revitalization Training (SMART) Program to promote cognitive health among patients with mild cognitive impairment (MCI), and the use of active mind strategy in preventing dementia among the older adults. The SMART Program consists of two components including, a community empowerment-educational campaign on active mind strategies for older adults, and a 24-week SUDOKU Training Programme for people with MCI.

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Key information

Conditions

Mild Cognitive Impairment Cognition Disorders Cognitive Dysfunction Mental Disorders Neurocognitive Disorders

Age range

55 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Medicine and Geriatrics, United Christian Hospital

Hong Kong

About this study

This study aims to implement a SMART Program to promote cognitive health among patients with MCI, and the use of active mind strategy in preventing dementia among the older adults. The SMART Program consists of two components including, a community empowerment-educational campaign on active mind strategies for older adults, and a 24-week SUDOKU Training Programme for people with MCI.

The community empowerment-educational campaign will be conducted in the elderly care centres of the two collaborating non-governmental organizations, with the purpose of increasing the awareness of people aged 55 or above on the importance of maintaining an active mind and preventing age-related cognitive decline and dementia. The campaign will include cognitive screening, poster exhibition, booth exhibition and individual counselling.

The SUDOKU training program include a 12-week face-to-face training session and a 12-week facilitated self-practice. The face-to-face sessions aim at developing the skills of the participants in solving the SUDOKU using the T-code. The 12-week training program will be evenly divided into three modules of increasing difficulty, with consideration given to the suboptimal cognitive function of the participants with MCI. These modules are developed by the Co-investigator who has rich prior experience in teaching older adults on SUDOKU puzzle.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • People with MCI as defined by a score of 19-26 out of the 30 on the Montreal Cognitive Assessment in the general public and aged 55 or above.

Exclusion criteria

  • Persons with dementia and communication problems will be excluded.

Treatment and study plan

24-week SUDOKU Training Programme

Behavioral

12-week face-to-face training session and a 12-week facilitated self-practice

Other names: SMART

Control Arm (wait-list)

Other

wait-list comparison group will receive the same program upon completion of the 6-month posttest evaluation on study outcomes

Primary outcomes

  1. Cantonese version of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)

    Time frame: Baseline

    To evaluate various domains of cognition

  2. Cantonese version of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)

    Time frame: 12-week

    To evaluate various domains of cognition

  3. Cantonese version of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)

    Time frame: 24-week

    To evaluate various domains of cognition

  4. The digit span-forward and backward test

    Time frame: Baseline

    To measure attention and working memory

  5. The digit span-forward and backward test

    Time frame: 12-week

    To measure attention and working memory

  6. The digit span-forward and backward test

    Time frame: 24-week

    To measure attention and working memory

  7. The list learning delayed recall test

    Time frame: Baseline

    To measure episodic memory

  8. The list learning delayed recall test

    Time frame: 12-week

    To measure episodic memory

  9. The list learning delayed recall test

    Time frame: 24-week

    To measure episodic memory

  10. Trail-Making Test Part A and B

    Time frame: Baseline

    To measure complex attention, executive function and task switching

  11. Trail-Making Test Part A and B

    Time frame: 12-week

    To measure complex attention, executive function and task switching

  12. Trail-Making Test Part A and B

    Time frame: 24-week

    To measure complex attention, executive function and task switching

Secondary outcomes

  1. Memory Inventory for Chinese

    Time frame: Baseline

    To evaluate the subjective memory impairment

  2. Memory Inventory for Chinese

    Time frame: 12-week

    To evaluate the subjective memory impairment

  3. Memory Inventory for Chinese

    Time frame: 24-week

    To evaluate the subjective memory impairment

  4. The 36-item Chinese version of the Short Form 36 (SF-36)

    Time frame: Baseline

    To measure Health-related quality of life in the participants

  5. The 36-item Chinese version of the Short Form 36 (SF-36)

    Time frame: 24-week

    To measure Health-related quality of life in the participants

Other outcomes

  1. 13-item satisfaction survey - for SMART Program

    Time frame: 12-week

    To evaluate the participant's satisfaction towards the Sudoku program including acceptability, applicability to promote brain health and psychosocial health, accessibility and level of support

  2. 10-item satisfaction survey - for community empowerment-educational campaign

    Time frame: 10-month

    To evaluate the participant's satisfaction towards this service component

Sponsors and collaborators

Lead sponsor

The University of Hong Kong

Other

Registry information

Official study title

New Wine in Old Bottle: the Effects of SUDOKU Mind Activation and Revitalizing Training (SMART) Program on Cognitive Function Among People With Mild Cognitive Impairment

Acronym: SMART

Important dates

Study start
2020
Primary completion
2023
Study completion
2023
First posted
Jun 4, 2021
Registry last updated
Jan 9, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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