Skip to main content
OpenTrials
Completed

NCT Number: NCT01884792

Effects of Standing on Glycemia in Prediabetic Adults

The study is a crossover, pilot trial examining the acute effects of standing on blood sugar in prediabetic, working adults. Participants will complete oral glucose tolerance testing, once while sitting and once while standing. They will also wear a continuous blood sugar monitor once while sitting at their desk for a week and once while using their desk as a sit-stand desk with a goal of standing intermittently for at least half of the work day. Physical activity levels will be measured with an accelerometer. The primary study hypothesis is that blood sugar will differ between the sitting and standing conditions for each of the tests performed.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

PreDiabetes Behavior Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases Prediabetic State Sedentary Behavior

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Human Services

Saint Paul, Minnesota, 55155, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Fasting blood glucose >100 mg/dl
  • Employed full-time working at least 35 hours/week
  • Able to safely begin a light physical activity program

Exclusion criteria

  • Heart disease
  • Renal disease
  • Peripheral neuropathy
  • Retinopathy
  • PAD
  • Lower limb amputation
  • pregnancy
  • active substance abuse
  • current smoker
  • psychiatric disorder
  • severe visual impairment
  • immune-compromised individuals,
  • enrollment in a physical activity study
  • use of insulin or an insulin pump

Treatment and study plan

Sitting OGTT

Other

Standing OGTT

Other

Sitting CGM

Other

Standing CGM

Other

Primary outcomes

  1. Blood sugar area under the curve

    Time frame: 2 hours

    The area under the curve following the 2 hour blood sugar tests.

Secondary outcomes

  1. Accelerometer counts

    Time frame: 4 hours and 2 5 day periods

    Accelerometer counts in the 4 testing conditions.

Sponsors and collaborators

Lead sponsor

University of Minnesota

Other

Collaborators

  • Mayo Clinic

Registry information

Official study title

Acute Effects of Standing on Glycemia in Prediabetic Adults: A Pilot Study

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Jun 24, 2013
Registry last updated
Sep 15, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.