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OpenTrials
Completed

NCT Number: NCT04571034

Effects of Roller Massage on Short-Term Passive Muscle Stiffness

Muscle stiffness is associated with a variety of variables that affect health, however there is limited research on the effect of massage on muscle stiffness, and existing research does not quantify the intensity of massage. Thus trial will determine the effect of roller massage on quadriceps muscle stiffness and passive range of motion.

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Key information

Conditions

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Kentucky

Lexington, Kentucky, 40536, United States

About this study

Following screening for eligibility and consent, subjects will be assigned randomly to one of three groups: a placebo control group and two roller massage groups (treatment groups). The treatment groups will each receive a single bout of roller massage. One treatment group will receive a massage at medium intensity (25 newtons of force directed perpendicular to surface of thigh), the other treatment group at high intensity (45 newtons of force directed perpendicular to surface of thigh). The placebo group will receive a single bout of sham ultrasound. Both placebo and treatments will be delivered to the anterior thigh with the participant in a supine position. Each procedure will last for 10 minutes. In all groups, muscle stiffness, natural oscillation frequency, elasticity, relaxation time, and creep at the vastus lateralis will be measured using a myotonometer. PROM for knee flexion will also be measured in both groups using goniometry. All measurements will be taken at 3 different times: immediately before treatment or placebo, immediately after treatment or placebo, and 30 minutes after treatment or placebo. Myotonometric measurements of the vastus lateralis will be taken 2/3 of the way down between the anterior superior iliac spine and lateral aspect of the patella, in accordance with guidelines for the Surface ElectroMyoGraphy for the Non-Invasive Assessment of Muscles. For goniometric measurement, participants will be in supine position on an examination table. The investigator will flex the participant's hip to 90 degrees and then, using a dynamometer (to ensure consistent applied force for all participants), flex the participant's knee. To measure knee flexion PROM, the goniometer will be positioned with the axis at the lateral epicondyle of the femur, the stationary arm in line with the lateral midline of the femur toward the greater trochanter, and the moving arm in line with the fibular head and lateral malleolus. During the time between the second and third measurements, subjects will be asked to sit quietly.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-Age 18-30

Exclusion criteria

  • Prior history of significant vascular or neuromuscular illness or impairment affecting the lower limbs
  • Serious injuries to the back or legs in the last six months
  • Discomfort or pain in the back or legs
  • Use of pain and anti-inflammatory medications
  • Any contraindications to massage treatment or ultrasound
  • Body mass index (BMI) >30 kg/m2.

Treatment and study plan

Sham Therapeutic Ultrasound

Procedure

A standard ultrasound machine (Vectratm by Chattanooga Group, Inc.) with inactive probe will be used to deliver sham massage.

Medium-Intensity Roller Massage

Procedure

This group will receive a single bout of roller massage at medium intensity (25 newtons of force directed perpendicular to the surface of the thigh).

High-Intensity Roller Massage

Procedure

This group will receive a single bout of roller massage at medium intensity (45 newtons of force directed perpendicular to the surface of the thigh).

Primary outcomes

  1. Change in Quadriceps Stiffness

    Time frame: 1 hour (at baseline, immediately after treatment and 30 minutes later)

    Quadriceps stiffness will be measured using a myotonometer at baseline, immediately after treatment, and 30 minutes later.

  2. Change in Passive Range of Motion

    Time frame: 1 hour (at baseline, immediately after treatment and 30 minutes later)

    Range of motion of the knee will be measured using a goniometer at baseline, immediately after treatment, and 30 minutes later.

Secondary outcomes

  1. Change in Quadriceps Natural Oscillation Frequency

    Time frame: 1 hour (at baseline, immediately after treatment and 30 minutes later)

    Quadriceps natural oscillation frequency will be measured using a myotonometer at baseline, immediately after treatment, and 30 minutes later.

  2. Change in Quadriceps Elasticity

    Time frame: 1 hour (at baseline, immediately after treatment and 30 minutes later)

    Quadriceps elasticity will be measured using a myotonometer at baseline, immediately after treatment, and 30 minutes later.

  3. Change in Quadriceps Relaxation Time

    Time frame: 1 hour (at baseline, immediately after treatment and 30 minutes later)

    Quadriceps relaxation time will be measured using a myotonometer at baseline, immediately after treatment, and 30 minutes later.

  4. Change in Quadriceps Creep

    Time frame: 1 hour (at baseline, immediately after treatment and 30 minutes later)

    Quadriceps creep will be measured using a myotonometer at baseline, immediately after treatment, and 30 minutes later.

Sponsors and collaborators

Lead sponsor

Jeffrey Sykora

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Sep 30, 2020
Registry last updated
Dec 9, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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