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Completed

NCT Number: NCT06813092

Effects of Resistance Exercise Compared to Whole-body Electromyostimulation in Young Female Dentists.

Due to their high workload and unfavorable working position, young female dentists are particularly at risk of cardiometabolic diseases and an early reduction in bone mineral density (BMD). With focus on the latter issue, short bouts of resistance exercise with high strain magnitude and velocity are commonly considered to be a feasible option to prevent bone loss in the early years of young adulthood. In parallel, whole-body electromyostimulation (WB-EMS) a trainings technology able address all main muscle groups simultaneously, however with dedicated exercise intensity might be a time-effective, joint friendly and safe option to maintain BMD in people unable or unmotivated to exercise conventionally. In the present study, we aim to compare the effects of a single session of WB-EMS versus high intensity, high velocity resistance exercise on biomarkers of bone formation (Procollagen type 1 N propeptide, P1NP) and resorption (C-terminal telopeptide of type I collagen, CTX-I). We hypothesize that no clinically relevant different effects on P1NP and CTX-I were determined.

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Key information

Age range

18 year–30 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Institute of Radiology, Erlangen, Germany

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • female dental students (>3rd semester) or licensed dentists
  • no competitive sports background for >2 years
  • normal body mass (BMI>18,5 and <25 kg/m2)

Exclusion criteria

  • more than one resistance exercise session per week (last 12 month)
  • whole-body electromyostimulation during the last 12 month
  • amenorrhea, oligomenorrhea

Treatment and study plan

Whole-Body Electromyostimulation

Other

20 min of WB-EMS (bipolar, 85 Hz, 350 µs, 6s impulse - 4s impulse break)

Resistance Exercise

Other

High-intensity/high velocity multiple set resistance exercise

Primary outcomes

  1. Changes for C-terminal telopeptide of type I collagen from pre- to 15 min post-exercise

    Time frame: Immediately pre-exercise to 15 min post exercise of a single exercise session

    Changes for C-terminal telopeptide of type I collagen (CTX-I) serum levels from pre- to 15 min post-exercise as determined by blood samples

Secondary outcomes

  1. Changes for Procollagen type 1 N propeptide from pre- to 15 min post-exercise

    Time frame: Immediately pre-exercise to 15 min post exercise of a single exercise session

    Changes for Procollagen type 1 N propeptide (P1NP) serum levels from pre- to 15 min post-exercise as determined by blood samples

  2. Changes for resting glucose from pre- to 15 min post-exercise

    Time frame: Immediately pr to 15 min post-exercise of a single exercise session

    Changes for resting glucose serum levels from pre- to 15 min post-exercise as determined by blood samples

  3. Changes for hemoglobin A1c from pre- to 15 min post-exercise

    Time frame: Immediately pre- to 15 min post-exercise of a single exercise session

    Changes for hemoglobin A1c (HBA1C) serum levels from pre- to 15 min post-exercise as determined by blood samples

Sponsors and collaborators

Lead sponsor

University of Erlangen-Nürnberg Medical School

Other

Registry information

Official study title

Effects of a Single Bout of High Intensity, High Velocity Resistance Exercise Compared to Whole-body Electromyostimulation on Cardiometabolic Risk Factors and Markers of Bone Formation and -Resorption in Young Female Dentists.

Acronym: FeDeBoMa

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 6, 2025
Registry last updated
Jan 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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