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OpenTrials
Active, Not Recruiting

NCT Number: NCT07716696

Effects of Pulmonary Rehabilitation Versus Standard Care in Patients With Pericarditis

Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life. Pulmonary rehabilitation is a structured intervention designed to improve respiratory function and overall physical performance. This study aims to compare the effectiveness of pulmonary rehabilitation versus standard care in improving clinical symptoms and functional outcomes in patients with pericarditis.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Pericarditis Anxiety Disorders Cardiovascular Diseases Chest Pain Cough Dyspnea Fatigue Heart Diseases Mental Disorders Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Tract Diseases Signs and Symptoms Signs and Symptoms, Respiratory

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

ULTH

Lahore, Punjab Province, Pakistan

About this study

This randomized controlled trial evaluates the comparative effectiveness of pulmonary rehabilitation and standard care in patients diagnosed with pericarditis. Participants are allocated into two groups: an intervention group receiving pulmonary rehabilitation and a control group receiving standard medical care.

Pulmonary rehabilitation includes breathing exercises, aerobic training, and patient education aimed at improving respiratory efficiency and reducing symptom burden. Such programs are widely used to improve functional capacity and quality of life in clinical populations [1].

Outcome measures include pain intensity, dyspnea, cough severity, fatigue, and anxiety, assessed using validated tools such as the Visual Analog Scale (VAS) and McMaster Cough Severity Questionnaire.

Assessments will be conducted at baseline and after completion of the intervention period.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed with pericarditis Age between 18-65 years Both male and female participants Medically stable Able to participate in rehabilitation Willing to provide informed consent

Exclusion criteria

Severe cardiovascular or respiratory instability Other major pulmonary diseases Recent surgery or trauma Neurological disorders affecting participation Unwillingness to participate

Treatment and study plan

Pulmonary Rehabilitation

Other

A structured program including breathing exercises, aerobic conditioning, and patient education administered over multiple weeks.

Standard care

Other

Routine clinical management as prescribed by the treating physician without additional rehabilitation protocol.

Primary outcomes

  1. Dyspnea Severity

    Time frame: Baseline and 8 weeks

    Measured using Visual Analog Scale (VAS)

Secondary outcomes

  1. Pain Intensity

    Time frame: Baseline and 8 weeks

    Measured using VAS

  2. Cough Severity

    Time frame: Baseline and 8 weeks

    Measured using McMaster Cough Severity Questionnaire

  3. Fatigue

    Time frame: Time Frame: Baseline and 8 weeks

    Measured using VAS or standardized fatigue scale

  4. Anxiety

    Time frame: Time Frame: Baseline and 8 weeks

    Measured using a validated anxiety scale

Sponsors and collaborators

Lead sponsor

University of Lahore

Other

Registry information

Official study title

Comparative Effects of Pulmonary Rehabilitation Versus Standard Care on Pain, Dyspnea, Cough Severity, Fatigue, and Anxiety in Patients With Pericarditis: A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 21, 2026
Registry last updated
Jul 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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