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Active, Not Recruiting

NCT Number: NCT06846164

Effects of Progressive Resistance Exercises Among Athletes With Hamstring Deficit After ACL Reconstruction

The goal of the study is to find out how mild home exercises (similar to usual care) and progressive strength training, which include neuromuscular exercise, affected knee joint function and HS muscle strength in individuals who has persistent HS muscle strength deficits 12-24 months after ACLR.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Sports Physical Therapy

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Innovative Health Concept

Lahore, 54770, Pakistan

About this study

The objective of the present study is to investigate whether individuals, who perform supervised progressive strength training including elements of neuromuscular exercise intervention (SNG) will achieve greater improvements in leg muscle power and greater improvements in knee function compared with individuals performing a homebased low-intensity weight-bearing exercise protocol. We hypothesize that supervised progressive strength training would be superior to a homebased low-intensity weight-bearing exercise protocol for regaining muscle strength and knee function. This study will impact society by promoting health, reducing healthcare costs, supporting productivity, and contributing to a more active and engaged community. Limited investigation exists regarding the durability of progressive resistance exercises in mitigating hamstring deficits post-ACL reconstruction and the personalized optimization of exercise protocols for individual athletes. Further exploration is needed for sustained benefits and tailored rehabilitation strategies.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 - 30 years
  • 12-24 months post-surgery (ACL reconstruction)
  • Persistent maximal isometric knee flexor strength asymmetry (>10% leg-to-leg the difference, in the isometric testing angle of 90° knee flexion)

Exclusion criteria

  • Body mass index [BMI] more than 35
  • known lower limb pathology (including previous and/or concomitant knee injuries requiring surgical intervention to either knee)

Treatment and study plan

Supervised progressive strength training including elements of neuromuscular exercise intervention (SNG)

Other

Participants will be randomized to SNG and will perform training sessions (60-70 minutes) twice weekly, over a duration of 12 weeks, commencing 8 exercises for the lower extremities in 3 sets of 10 repetitions with an intensity of 12 repetitions maximum. Individual progression, quality of exercise, number of sets, repetitions, and additional training weights will be monitored

home based low-intensity weight-bearing exercise protocol.

Other

Participants allocated to CON will receive written and verbal instructions regarding 4 home-based (low intensity), weight-bearing exercises for the lower extremities, to be performed twice weekly. This intervention is designed to resemble usual care in cases where persistent knee muscle strength deficits would be discovered and considered a clinical issue.

Primary outcomes

  1. Limb Symmetry Index

    Time frame: 12 weeks

    It is used for knee extensors and flexors strength. It is the strength ratio between the injured and uninjured knees. It is a common method of assessing strength and functional performance after ACLR.

Secondary outcomes

  1. H/Q ratio

    Time frame: 12 weeks

    it is used to detect muscle imbalance, monitor knee joint stability, and indicate lower extremity injury prevention and rehabilitation.

Other outcomes

  1. KOOS questionnaire

    Time frame: 12 weeks

    It is used to assess five outcomes: pain, activity of daily living, sport and recreation function, and knee-related quality of life.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects of Progressive Resistance Exercises on Range of Motion & Strength and Function Among Athletes With Hamstring Deficit After ACL Reconstruction

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Feb 25, 2025
Registry last updated
Feb 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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