Skip to main content
OpenTrials
Completed

NCT Number: NCT05262933

Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia

The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating conditions. However spinal anesthesia has some complications as hypotension, bradycardia and Post Dural Puncture Headache (PDPH). A practical strategy for avoiding hypotension during initiation of spinal anesthesia for cesarean delivery includes intravenous crystalloid, in conjunction with administration of vasopressors. PDPH is one of the most frequent complications of spinal anesthesia. Conservative therapies such as bed rest, hydration, and caffeine are commonly used as management. For this study, coffee group of patients will be given unsweetened brewed coffee 150 ml until 2-4 hours before surgery. Patients who accept to drink brewed coffee ( coffee group) and water( control group) will be included in the study. The patient's heart rate, blood pressure, oxygen saturation will be monitored and recorded during operation. Intraoperative will be recorded to amount of vasopressor and intraveous crystalloid. Whether the patient develops PDPH in the postoperative period will be followed for 3 days. In addition abdominal auscultation for bowel sounds hourly and the time of first bowel movements will be recorded. According to the patient's statement, the time of first flatulence and defecation will be followed and recorded.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Erciyes University

Kayseri, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients who accept to participate in the study
  • patient who limit the consumption of caffeinated beverages such as coffee and tea during pregnancy
  • Patients with known caffeine or coffee allergy

Exclusion criteria

  • patients who refuse to participate in the study
  • Patients with known cardiovascular disease
  • Patients with known cerebrovascular disease
  • patients with known neurological, neurodegenerative or psychiatric disease
  • patients with known liver failure
  • patient followed up with eclampsia and preaclampsi
  • higher number of needle passes in spinal anesthesia
  • patients treated with an antiemetic

Treatment and study plan

Coffee

Other

It will be given to patients brewed coffee to drink and evaluated to hypotension and post spinal puncture headache

Other names: It will be given to patients brewed coffee to drink

Water

Other

It will be given to patients water to drink and evaluated to hypotension and post spinal puncture headache

Other names: It will be given to patients water to drink

Primary outcomes

  1. hypotension

    Time frame: intraoperative time period

    effects of orally coffee intake on spinal anesthesia induced hypotension

Secondary outcomes

  1. Post-dural puncture headache

    Time frame: post operative 3 days

    Effects of orally coffee intake on postdural puncture headache

  2. intestinal motility, first flatus

    Time frame: post operative 3 days

    Effects of orally coffee intake on postoperative intestinal motility

Sponsors and collaborators

Lead sponsor

TC Erciyes University

Other

Registry information

Official study title

Effect of Preoperative Coffee Consumption on Intraoperative and Post Operative Outcomes in Cesarean Section With Spinal Anesthesia

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Mar 2, 2022
Registry last updated
May 16, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.