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OpenTrials
Completed

NCT Number: NCT02814188

Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses

Carbohydrate ingestion, in particular fructose, has been shown in a handful of previous studies to elicit a thermic effect and increase core body temperature after ingestion. Carbohydrate foods and supplements are commonly consumed prior to endurance running competition, including situations where an athlete's ability to dissipate body heat is compromised. Thus, there is some potential for pre-exercise carbohydrate ingestion to have a deleterious effect on body heat regulation in hot and humid environments. Thus, this projects aims to study the effects of pre-exercise carbohydrate ingestion on core body temperature, perceived thermal stress, and perceived exertion during high-intensity running.

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Key information

Conditions

Impaired Thermoregulation Behavior Motor Activity

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Human Performance Laboratory

Norfolk, Virginia, 23529, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be currently running ≥20 miles per week
  • Have a projected 5-km maximal effort running time between 16:00-23:00 minutes

Exclusion criteria

  • Any gastrointestinal disorders that cause swallowing problems or frequent nausea/vomiting

Treatment and study plan

Carbohydrate Beverage

Other

750 ml of a 13.5% carbohydrate (sucrose) beverage

Placebo beverage

Other

750 ml of an artificially-sweetened beverage

Primary outcomes

  1. Core Body Temperature

    Time frame: 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)

    Core body temperature will be measured with a ingestible pill thermometer. Readings will be taken during a 60 minute rest period and at 1-km intervals during a 5-km run.

Secondary outcomes

  1. Thermal Sensation Scale

    Time frame: 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)

    The Thermal Sensation Scale is a 0-8 numerical rating scale with descriptors of "unbearably cold" at 0, "neutral" at 4, and "unbearably hot" at 8. These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run.

  2. Feeling Scale

    Time frame: 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)

    The Feeling Scale is a bipolar numerical rating scale ranging from -5 to +5, with descriptors of "very bad" at -5, "neutral" at 0, and "very good" at +5. These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run.

  3. Rating of Perceived Exertion

    Time frame: 80 minutes (60, 50, 40, 30, 20, and 10 min pre-run and at 1-km intervals during a 20 min 5-km run)

    These ratings will be collected during a 60 minute rest period and at 1-km intervals during a 5-km run.

Sponsors and collaborators

Lead sponsor

Old Dominion University

Other

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Jun 27, 2016
Registry last updated
Dec 15, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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