Skip to main content
OpenTrials
Completed

NCT Number: NCT07398248

Effects of Powerlifting-Based Training in Athletes

This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. The training program will be implemented for a specific period, and relevant blood parameters will be evaluated before and after the intervention. The findings of this study may contribute to a better understanding of the physiological effects of weightlifting-based training on athletes.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Physical Fitness Hormonal Response Metabolic Parameters

Age range

18 year–24 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Sport Sciences, Tunceli, Center, Turkey (Türkiye)

Loading trial locations.

About this study

This study is designed as a randomized controlled trial to investigate the effects of a structured weightlifting training program on hormonal, metabolic, and lipid profile parameters in athletes. Eligible participants will be randomly assigned to either an intervention group undergoing a weightlifting-based training protocol or a control group continuing their usual training routines.

The intervention will be implemented over a predetermined training period, and outcome measures will include selected hormonal, metabolic, and lipid profile markers obtained from blood samples. Measurements will be taken at baseline and at the end of the training period. The results of this study are expected to provide evidence on physiological adaptations associated with weightlifting-based training and offer practical implications for training program design in athletic populations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male basketball players aged 18 to 24 years
  • At least two years of regular sports experience
  • Actively participating in basketball training and competition
  • Voluntary participation with written informed consent

Exclusion criteria

  • History of musculoskeletal injury or surgery within the last six months
  • Presence of chronic disease or metabolic disorder
  • Use of performance-enhancing drugs or hormonal supplements
  • Participation in another structured training program during the study period

Treatment and study plan

Powerlifting-Based Training

Other

Participants will perform a structured powerlifting-based training program including squat, bench press, and deadlift exercises, conducted 3 sessions per week for 8 weeks under supervision.

Usual Basketball Training

Other

Participants continued their usual basketball training routines without any additional strength or powerlifting-based exercises.

Blood Sampling and Laboratory Analysis

Other

Venous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer.

Primary outcomes

  1. Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting serum total testosterone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  2. Mean Change in Fasting Serum Cortisol Concentration Measured by ELISA (µg/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting serum cortisol concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  3. Mean Change in Fasting Serum Growth Hormone Concentration Measured by ELISA (ng/mL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting serum growth hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  4. Mean Change in Fasting Serum Thyroid-Stimulating Hormone Concentration Measured by ELISA (µIU/mL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting serum thyroid-stimulating hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  5. Mean Change in Fasting Serum Triiodothyronine Concentration Measured by ELISA (ng/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting serum triiodothyronine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  6. Mean Change in Fasting Serum Thyroxine Concentration Measured by ELISA (µg/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting serum thyroxine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

Secondary outcomes

  1. Mean Change in Fasting Serum Insulin Concentration Measured by ELISA (µIU/mL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting serum insulin concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA).

  2. Mean Change in Fasting Blood Glucose Concentration Measured by Automated Biochemical Analyzer (mg/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention fasting blood glucose concentrations, measured from venous blood samples using an automated biochemical analyzer.

  3. Mean Change in Total Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention total cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.

  4. Mean Change in Low-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention low-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.

  5. Mean Change in High-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention high-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer.

  6. Mean Change in Triglyceride Concentration Measured by Automated Biochemical Analyzer (mg/dL)

    Time frame: Baseline and post-intervention (8 weeks)

    Mean difference between baseline and post-intervention triglyceride concentrations, measured from venous blood samples using an automated biochemical analyzer.

Sponsors and collaborators

Lead sponsor

Ramazan Erdoğan

Other

Registry information

Official study title

The Effects of Powerlifting-Based Training on Hormonal, Metabolic, and Lipid Profile Parameters in Athletes: A Randomized Controlled Trial

Acronym: PLBT-ATH

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 9, 2026
Registry last updated
Feb 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.