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Completed

NCT Number: NCT02692612

Effects of Power-velocity Muscle Characteristics During Ageing

The purpose of this project is to investigate the age-related differences in force-velocity muscle characteristics during isolated knee extensions variable in speed and load, during cyclic movements on a usual and recumbent bike variable in speed and velocity development and a functional test battery with healthy participants aged between 20-80 years.

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Key information

Conditions

Sarcopenia Atrophy Muscular Atrophy Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of kinesiology and rehabilitation sciences

Leuven, 3000, Belgium

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy volunteers age 20 to 80 years

Exclusion criteria

  • Knee or hip prothesis
  • Systematic training
  • Cardiovascular disease
  • Acute lower back pain
  • Acute knee pain
  • Dementia

Treatment and study plan

Primary outcomes

  1. Differences in power-velocity characteristics during ageing

    Time frame: 1x at baseline (cross sectional study)

    peak power and rate of power development (slope) at different velocities during knee extension movement and cyclic multijoint leg press movement compared between young and old people

Secondary outcomes

  1. Reliability of strength tests on regular and recumbent bike.

    Time frame: 1x at baseline (cross sectional study)

    reliability of peak power and rate of power development outcomes measured twice within a period of 2 weeks

  2. Differences in muscle fascicle characteristics during ageing.

    Time frame: 1x at baseline (cross sectional study)

    Differences between young and old people of fascicle shortening velocity during dynamic leg press movements measured via dynamic ultrasound

  3. Differences in muscle activation during ageing.

    Time frame: 1x at baseline (cross sectional study)

    Differences in muscle activation pattern during dynamic leg press movements measured via muscle electromyography

Sponsors and collaborators

Lead sponsor

Universitaire Ziekenhuizen KU Leuven

Other

Registry information

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Feb 26, 2016
Registry last updated
May 19, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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