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Completed

NCT Number: NCT07192796

Effects of Pilates and Neuromuscular Exercises on Postural Control in Dynamic Knee Valgus

This randomized controlled trial aims to investigate the effects of neuromuscular and Pilates exercise programs compared with a control group in young adults with dynamic knee valgus (DKV). Thirty-six participants were randomly assigned to neuromuscular, Pilates, or control groups. The intervention groups completed a supervised exercise program three times per week for six weeks (18 sessions).

The primary outcome is the frontal plane projection angle (FPPA) during single-leg tasks. Secondary outcomes include muscle strength, balance, and vertical jump performance.

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Key information

Age range

18 year–24 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Atlas University

Istanbul, Kagıthane, 34403, Turkey (Türkiye)

About this study

This prospective, single-blind randomized controlled trial was designed to evaluate the comparative effects of Pilates and neuromuscular exercise training on lower extremity alignment and postural control in young adults with dynamic knee valgus (DKV). Ethical approval was obtained from the Istanbul Atlas University Non-Interventional Scientific Research Ethics Committee (Approval No: E-22686390-050.99-41964, 03/05/2024).

A total of 45 participants aged 18-24 years, all right-leg dominant, were initially enrolled and randomized into three groups: Pilates, neuromuscular exercise, and control (15 in each group). Randomization was performed using computerized allocation. Due to dropouts, 36 participants (12 per group) completed the study between June and August 2024.

The interventions consisted of a 6-week supervised program (18 sessions, 3 times per week). Both Pilates and neuromuscular protocols were progressive in intensity, incorporating resistance bands, core stabilization, and functional balance exercises. The control group did not receive any intervention but underwent the same baseline and post-intervention assessments.

The primary outcome was the frontal plane projection angle (FPPA) during single-leg squat and single-leg drop jump tasks, measured using 2D video analysis.

The secondary outcomes included:

Isometric strength of the gluteus medius and rectus femoris measured with a handheld dynamometer,

Balance performance assessed separately by the Biodex Postural Stability Test (overall, anterior-posterior, and medial-lateral stability indices) and the Limits of Stability Test,

Functional performance assessed by the OptoJump system, including vertical jump height, vertical jump power, and reactive strength index.

All assessments were conducted at baseline and after 6 weeks by the same physiotherapist to ensure intra-rater reliability.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • having asymptomatic dynamic knee valgus
  • being between 18 and 24 years of age
  • having no medical history, a body mass index (BMI) between 18 and 24
  • no history of orthopedic, neurological, vascular, systemic, or rheumatic diseases
  • no complaints of pain in any part of the body during physical activities
  • the ability to communicate in Turkish (both written and verbal)

Exclusion criteria

  • individuals with hip anteversion or retroversion or other postural disorders affecting knee kinematics, those unable to perform the exercises as demonstrated, those experiencing pain during exercises (VAS >5)
  • individuals with a history of orthopedic surgery, those with strength deficits between extremities
  • the presence of cognitive or psychological disorders that could hinder cooperation
  • pregnancy or suspected pregnancy
  • sleep disorders, regular medication use, intake of painkillers, sedatives, or psychiatric drugs within the last 24 hours
  • history of chronic systemic, rheumatologic, neurological, or vascular diseases

Treatment and study plan

Pilates Exercise Program

Behavioral

A 6-week supervised Pilates exercise program, with 18 sessions. Exercises focused on core stabilization, posture, and lower limb alignment using mat-based and resistance band movements.

Neuromuscular Exercise Program

Behavioral

A 6-week supervised neuromuscular training program, 18 sessions . Training emphasized balance, proprioception, dynamic stability, and strengthening of lower extremity muscles.

Primary outcomes

  1. Frontal Plane Projection Angle (FPPA)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    Participants performed a single-leg vertical drop jump from a 20 cm platform with the dominant leg while keeping their hands on the waist. Knee valgus angle at landing was recorded using 2D video analysis with a camera placed 3 m in front at a height of 45 cm.

Secondary outcomes

  1. Isometric Strength of Gluteus Medius

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    Isometric strength of the gluteus medius muscle was measured using the PowerTrack-II handheld dynamometer in a standardized side-lying position.

  2. Isometric Strength of Rectus Femoris

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    Isometric strength of the rectus femoris muscle was measured using the PowerTrack-II handheld dynamometer in a standardized seated position with 90° knee flexion.

Other outcomes

  1. Postural Stability Test - Overall Stability Index (Biodex)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    Overall stability index from the Biodex Postural Stability Test was recorded to evaluate total postural control.

  2. Postural Stability Test - Anterior-Posterior Stability Index (Biodex)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    The anterior-posterior stability index was measured with the Biodex Postural Stability Test to assess directional balance control.

  3. Postural Stability Test - Medial-Lateral Stability Index (Biodex)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    The medial-lateral stability index was measured with the Biodex Postural Stability Test to assess directional balance control.

  4. Limits of Stability Test (Biodex)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    Limits of Stability test measured weight-shifting ability toward illuminated targets using the Biodex Balance System.

  5. Vertical Jump Height (OptoJump)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    Vertical jump height was assessed using the OptoJump system during single-leg vertical jump tasks.

  6. Vertical Jump Power (OptoJump)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    Vertical jump power was measured using the OptoJump system to evaluate lower extremity explosive strength.

  7. Reactive Strength Index (RSI, OptoJump)

    Time frame: At baseline (Day 1) and following completion of 6 weeks of intervention (Week 6)

    RSI was calculated using the OptoJump system to assess neuromuscular efficiency during jump tasks.

Sponsors and collaborators

Lead sponsor

Şebnem Nur Alkan

Other

Registry information

Official study title

Comparative Effects of Pilates and Neuromuscular Exercises on Postural Control in Dynamic Knee Valgus

Acronym: DKV-EX

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Sep 25, 2025
Registry last updated
Sep 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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