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OpenTrials
Completed

NCT Number: NCT05032612

Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis

The purpose of this study is to evaluate the effects of photobiomodulation (PBM) on postoperative pain after endodontic treatment in mandibular molar teeth diagnosed with symptomatic apical periodontitis.

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Key information

Conditions

Postoperative Pain Jaw Diseases Mouth Diseases Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Periapical Diseases Periapical Periodontitis Periodontal Diseases Periodontitis Postoperative Complications Signs and Symptoms Stomatognathic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Posterior mandibular molars
  • No previous root canal therapy on the tooth in question
  • Able to complete the endodontic treatment in one visit

Exclusion criteria

  • Maxillary teeth, mandibular anteriors and premolars
  • Infection (swelling, sinus tract) on the tooth in question
  • Periodontal disease on the tooth in question
  • Dental trauma
  • Crown/ root fractures
  • Systemic diseases
  • Immunocompromised patients

Treatment and study plan

PBM Therapy

Device

After the endodontic treatment, PBM therapy will be performed using a 660 nm diode laser (SiroLaser Advance Plus, Dentsply Sirona Inc, Charlotte, NC, USA), with an 8mm tip diameter.The laser tip will be placed on the following external surfaces in a contact mode: mesiobuccal, distobuccal, mesiolingual and distolingual . The power output of the laser will be 50mW and will be verified by Power Meter (PM600 Power/Energy meter, Molectron Detector Inc, Portland, OR, USA). Each site will be irradiated for 25 s with an energy density of 10 J/cm2 .

PBM Sham

Device

For the PBM sham similar procedure as PBM therapy will be performed without activating the laser.

Primary outcomes

  1. Pain as Assessed by the Visual Analog Scale

    Time frame: 72 hours after treatment

    This scale ranges form 0(no pain) to 10(worst pain)

Secondary outcomes

  1. Pain as Assessed by the Visual Analog Scale

    Time frame: 0 hours, 6 hours, 12 hours and 24 hours hours after treatment

    This scale ranges form 0(no pain) to 10(worst pain)

Sponsors and collaborators

Lead sponsor

The University of Texas Health Science Center, Houston

Other

Registry information

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Sep 2, 2021
Registry last updated
Mar 24, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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