Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

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Key information

Conditions

Patellar Tendinopathy / Jumpers Knee

Age range

18 year–55 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Institute of Sports Medicine Copenhagen. Dept 8 1st floor. Bispebjerg Hospital

Copenhagen, 2400, Denmark

About this study

3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity.

Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI.

Treatment satisfaction will be stated after intervention period.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Clinical patellar tendinopathy pain.
Tendon swelling
Hypoechoic
Doppler activity in tendon

Exclusion criteria

Previous knee surgery
diabetes
arthritis
previous steroid injections

Treatment and study plan

peritendinous corticosteroid injections

Procedure

1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational

eccentric decline squat training

Procedure

eccentric decline unilateral squats performed twice daily. for 12 weeks

heavy slow resistance training

Procedure

Heavy slow resistance training for knee extensors. 3/week. total of 12 weeks

Sponsors and collaborators

Lead sponsor

Bispebjerg Hospital

Other

Registry information

Important dates

Study start: 2006
Study completion: 2007
First posted: Nov 28, 2006
Registry last updated: May 22, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed