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NCT Number: NCT06183541

Effects of Pericapsular Nerve Group Block Applied in Patients Undergoing Hip Fracture Surgery.

In this study, it was aimed to compare the multimodal analgesia application or the pericapsular nerve group (PENG) block methods in patients undergoing hip surgery. The effectiveness and benefit rate of the PENG block in postoperative pain will be evaluated.

Postoperative pain, need for additional analgesia, range of motion of the hip joint, mobilization time, length of hospital time and adverse events in patients undergoing hip fracture surgery with and without PENG block will be investigated.

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Key information

Age range

30 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Umraniye Education and Research Hospital, Istanbul, Umraniye, Turkey (Türkiye)

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About this study

This prospective randomised controlled study included a total of 70 patients aged 30-85 years who underwent hip fracture surgery under spinal anaesthesia. Patients were randomly divided into two groups using the sealed envelope method, Group I: those who received PENG block (n:35) and Group II:Those who did not receive PENG block (control group) (n: 35).

All patients will undergo hip fracture surgery by the same surgical team. Each patient will be informed about the procedure to be performed during anesthesia and surgery, and signed informed consent will be obtained before the procedure.Patients in Group I who will undergo the PENG block method; Before surgery, after spinal anesthesia, PENG block is performed under sterile conditions under ultrasonography guidance. With the patient supine, a 2-5 MHz, low-frequency, curvilinear probe is placed in the transverse plane medial to the anterior inferior iliac spine (AIIS), with the medial end of the probe rotated approximately 45° counterclockwise to align with the superior pubic ramus.

With the PENG block, an 80 mm block needle is placed in the fascial plane between the psoas tendon and the pubic ramus and 20 ml of 0.5% bupivacaine is administered.

As for the patients in Group II (control group); It is a routine practice at the end of surgery; 10 ml 0.5% bupivacaine + 10 ml 2% lidocaine is infiltrated into the surgical area by the surgical team.

For routine postoperative multimodal analgesia, intravenous PCA (patient controlled analgesia) was administered to patients in both groups with tramadol 50 mg at a basal rate of 10 mg / hour after loading (20 mg bolus dose + 30 minutes lock time) and paracetamol 10 mg / kg iv. (Given every 8 hours)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who will undergo hip fracture surgery Women and men aged 30-85

Exclusion criteria

  • Patients under 30 years old, over 85 years old
  • American Society of Anesthesiology (ASA) IV,
  • Those with cognitive impairment (alzheimer, dementia, delirium, etc.)
  • Those with application site infection
  • Those who are allergic to local anesthetic substances
  • Patients are non-consenting patients.

Treatment and study plan

pericapsular nerve group (PENG) block

Procedure

Pericapsular nerve group (PENG) block The femoral nerve and obturator nerve terminal branches, which provide sensory innervation of the hip joint, are blocked, thus providing analgesia without creating a motor block.

Primary outcomes

  1. postoperative pain score

    Time frame: 30 min, 12th, 24th and 48th hours in the postoperative period

    VAS pain score

  2. Total opioid consumption

    Time frame: postoperative 48 hours

    Tramadol (mg)

  3. mobilisation time

    Time frame: postoperative 24-48 hours

    take 5 steps with walker

Secondary outcomes

  1. PENG block adverse events

    Time frame: between the time surgery starts and the 48th hour

    motor block, nerve damage, hypotension, bradycardia

  2. length of hospital stay

    Time frame: between the time of hospitalization for the operation and discharge (day)

    day

Study contacts

Contact information is provided by the study sponsor or research team.

Hale Arkan Tuna, MD

CONTACT

[email protected]

+905303705619

Zeliha Tuncel, MD

CONTACT

[email protected]

+905053577483

Sponsors and collaborators

Lead sponsor

Umraniye Education and Research Hospital

Other Gov

Registry information

Official study title

Effects of Pericapsular Nerve Group (PENG) Block Applied for Analgesia on the Postoperative Process in Patients Undergoing Hip Fracture Surgery.

Important dates

Study start
2023
Primary completion
2025
Study completion
2026
First posted
Dec 27, 2023
Registry last updated
Nov 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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