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NCT Number: NCT07614464

Effects of Obesity on Physical Abilities and Daily Living Activities in Elderly Adults

Obesity is a significant health problem whose prevalence has tripled worldwide in the last fifty years, also involving older people. Older people present sarcopenia, characterized by the progressive loss of muscle mass and strength. Sarcopenia, accompanied by an increase in adipose tissue, causes a specific condition called sarcopenic obesity. The increase in adipose tissue and the decrease in muscle mass determines a reduction in strength and physical abilities necessary to perform everyday activities of daily living in obese older people.

To understand how the condition of excess adipose tissue influences the activities of daily living of older people with obesity, it is necessary to compare the physical abilities, body composition, and results of various motor skills with normal-weight subjects, corrected for sex and age.

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Key information

Conditions

Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Sarcopenic Obesity Signs and Symptoms

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Istituto Auxologico Italiano IRCCS, Site Piancavallo

Oggebbio, 28824, Italy

Location status: Recruiting

Location contact

Alessandro Sartorio, MD

CONTACT

[email protected]

+39-02619111 ext. 2624

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Obese elderly:

Inclusion criteria

  • Both sexes
  • Body Mass Index > 35 kg/m2
  • Age > 65 years
  • Hospitalized for a 3-week integrated metabolic rehabilitation program

Exclusion criteria

  • Absence of signed informed consent

Normal weight elderly:

Inclusion criteria

  • Both sexes
  • Body Mass Index 20-25 kg/m2
  • Age > 65 years
  • Attendance of healthy lifestyle program in their home town

Exclusion criteria

  • Absence of signed informed consent

Treatment and study plan

Fitness tests and questionnaires

Other

Anthropometric measurements, physical fitness tests and daily life questionnaires

Primary outcomes

  1. Fat mass

    Time frame: Baseline

    Fat mass as assessed by bioelectrical impedance

  2. Lean mass

    Time frame: Baseline

    Lean mass as assessed by bioelectrical impedance

  3. Barthel Index

    Time frame: Baseline

    Level of independence in 10 basic daily activities (ADLs) Total score ranges from 0 to 100

  4. Handgrip test

    Time frame: Baseline

    Score in kilograms (kg) using a hand dynamometer

Study contacts

Contact information is provided by the study sponsor or research team.

Alessandro Sartorio, MD

CONTACT

[email protected]

+3902619111 ext. 2426

Luca Grappiolo, Dr

CONTACT

[email protected]

+3902619111 ext. 2894

Sponsors and collaborators

Lead sponsor

Istituto Auxologico Italiano

Other

Registry information

Acronym: CAPFISOBEANZ

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 29, 2026
Registry last updated
May 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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