U.S. Army Aeromedical Research Laboratory
Fort Rucker, Alabama, 36362, United States
NCT Number: NCT04155333
Non-invasive brain stimulation has been shown to alter performance in both clinical and healthy populations on cognitive tasks. While the performance alterations have generally been shown to result in enhancement, mixed results remain in the literature. Much of the mixed results within the literature have been attributed to the use of different stimulation parameters, targeting of different brain areas, and using a variety of performance measures or assessing different constructs. However, non-invasive brain stimulation is a desirable method for enhancing Soldier performance given the ease of administration and minimal side effects as compared to other forms of performance enhancement (e.g., pharmaceuticals, caffeine). The objective of the current study is to evaluate the effects of non-invasive brain stimulation to the left dorsolateral prefrontal cortex in enhancing Soldier cognitive skills and performance on military tasks. A double blind within-subjects design will be used with healthy, rested Soldiers who will receive non-invasive brain stimulation and perform basic cognitive and operationally relevant tasks.
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Notify Me18 year–40 year
All sexes
Interventional
Not applicable
Fort Rucker, Alabama, 36362, United States
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation that stimulates the brain through the application of a low-intensity electrical current, typically ranging from 1 to 2 milliamps (mA), via electrodes placed on an individual's scalp. During the active stimulation sessions, 2 mA of stimulation will be applied for 30 minutes. During the sham stimulation session, 2 mA of stimulation will be applied over the course of 90 sec, the electrodes will remain in place for the 30 minute duration.
Time frame: Folllowing stimulation; task lasts approximately 20 min
Patrol exertion multitask
Time frame: Folllowing stimulation; task lasts approximately 40 min
Target acquisition
Time frame: Approximately 3 minutes during stimulation
Stroop test
Time frame: Approximately 5 minutes during stimulation
Dual n-back
Time frame: Approximately 2 minutes during stimulation
Digit span task
Time frame: Approximately 7 minutes during stimulation
Rapid Visual Information Processing Task
Time frame: Approximately 2 minutes during stimulation
Shifting Attention Task: Digit symbol substitution task
Time frame: Approximately 3 minutes after stimulation
Stop signal task - response inhibition
Time frame: Approximately 1 minute after stimulation
Delayed Discounting Task
Time frame: Approximately 5 minutes after stimulation
Uses Task
Time frame: Approximately 1 minute, before and after stimulation
Karolinska Sleepiness Scale
Time frame: Approximately 15 minutes during intake
Morningness-Eveningness Questionnaire
Time frame: Approximately 15 minutes during intake
Shipley's Institute of Living Scale
Time frame: Approximately 10 minutes during intake
Behavioral Avoidance/ Inhibition Scales
Time frame: Approximately 3 minutes before and after stimulation
Profile of Mood States - Short Form
Time frame: Approximately 2 minutes before and after stimulation
Symptom Checklist
Time frame: Approximately 5 minutes before and after stimulation
Welch Allyn Connex 6000
United States Army Aeromedical Research Laboratory
Fed
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