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Completed

NCT Number: NCT05525871

Effects of Nitrates and Citrulline Malate on Performance in Professional Professional Soccer

Randomized, single-center, parallel, team-stratified, stratified experimental study to evaluate the efficacy of a high sports supplement in improving high-intensity intermittent exercise performance in professional female soccer players.

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Key information

Conditions

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Catholic University of Murcia

Murcia, 30107, Spain

About this study

Subjects who meet the selection criteria will be randomly assigned to each of the study groups (investigational product or placebo, depending on the group to which they have been assigned).

The product to be consumed will be Nitrates and Citrulline Malate. Participants will consume the product for 30 days. The intake should be done two hours before each training session and the same dose will be consumed.

The women's soccer players will perform a stress test with gas analysis to measure performance, as well as a Wingate test without consumption of the products. Five days later, the players will perform the Yo-Yo IR1 test in the field and will repeat the same tests performed at the beginning of the test after product consumption.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Present at the time of signing the informed consent at the age between 18 and 40 years.
  • Female.
  • Healthy subjects without any chronic disease.
  • Volunteers capable of understanding the clinical study, willing to give their written informed. consent and comply with the procedures and requirements of the study. and requirements of the study.

Exclusion criteria

  • Players who change teams during the experimental study.
  • Smoking subjects.
  • Subjects using mouthwashes during the study.
  • Subjects with a history of drug, alcohol or other substance abuse or other factors that limit their ability to cooperate during the study. factors that limit their ability to cooperate during the study.
  • Subjects whose status makes them ineligible for the study, at the discretion of the investigator discretion of the investigator.

Treatment and study plan

Nitrates and Citrulline Malate

Dietary Supplement

Female soccer players should consume the experimental product for 30 days to evaluate the efficacy of a sports supplement high in nitrates combined with citrulline malate in the improvement of performance in high-intensity intermittent exercise.

high intensity

Control product

Dietary Supplement

Fruit puree

Primary outcomes

  1. Aerobic and anaerobic thresholds - VO2max

    Time frame: Change in initial maximal oxygen consumption at 30 days

    Measured with a gas analyzer

  2. Fatigue in jumping

    Time frame: Change in initial jump fatigue at 30 days

    Measured with a contact platform

  3. Anaerobic capacity

    Time frame: Change in baseline anaerobic capacity at 30 days

    Measured with a Monark cycloergometer

Secondary outcomes

  1. Microcapillary blood

    Time frame: It will be measured on two different occasions. Day one and 30 days later.

    This test provides biochemical variables (ABL90FLEX) with 70 ml of capillary blood.

  2. Lactate

    Time frame: It will be measured on two different occasions. One on the first day (without intake of product ) and 30 days later, the same measurements but after having consumed the product

    Lactate levels will be measured using the Lactate Pro

  3. Safety variables

    Time frame: It will be measured on two different occasions. Day one and 30 days later.

    It is a blood test that measures the presence of some enzymes, proteins and bilirubin in the blood, with the aim of determining if there is any alteration in the liver.

Sponsors and collaborators

Lead sponsor

Universidad Católica San Antonio de Murcia

Other

Registry information

Official study title

Experimental Study to Evaluate the Effects of Effects of a Sports Supplement Based on Nitrates and Citrulline Malate on Performance in Professional Soccer Players

Acronym: NiCiFut

Important dates

Study start
2022
Primary completion
2022
Study completion
2023
First posted
Sep 2, 2022
Registry last updated
Nov 27, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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