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Completed

NCT Number: NCT05529914

Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis

A randomized control trial will be conducted at the outpatient department of Dow Institute of Physical Medicine and Rehabilitation. A sample size of 80 is calculated using PASS version 11 software. The subjects will be first screened and those who fulfill the inclusion criteria, will be asked to fill the consent form. After selection, the participants will be randomly allocated by the help of computer generated randomization sheet, into two groups i.e. experimental and the control group. The group A will be provided with the myofascial release along with the neuromuscular training whereas the group B will only receive the neuromuscular training. Cold pack will be applied to both the groups. The neuromuscular training consists of warm-up phase, lunges, sideways exercises, wall squats, weight transfer exercises, step up and down and the cool down phase. Total 12 sessions of 35 minutes each will be given to all the participants for about 4 weeks on alternate days. Outcome measures will be analyzed by visual analogue scale (VAS) for pain assessment, goniometry for range of motion and the Knee injury and Osteoarthritis Outcome Score (KOOS) to evaluate the functional assessment of the patients at the baseline and the post intervention.

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Key information

Conditions

Knee Osteoarthritis Arthritis Bursitis Joint Diseases Musculoskeletal Diseases Osteoarthritis Osteoarthritis, Knee Pes Anserine Bursitis Rheumatic Diseases

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dow Institute of Physical Medicine and Rehabilitation, Karachi, Sindh, Pakistan

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and Females both with the age between 40-60 years.
  • Patients with unilateral or bilateral knee osteoarthritis with pes anserine syndrome.
  • Patients with knee pain more than 3.4 cm on visual analogue scale as minimum cut of value.
  • Kellgren and Lawrence grade II and III on radiological findings.
  • Duration of knee osteoarthritis more than 3 months (chronic).

Exclusion criteria

  • Patients with any neurological disorder.
  • Knee deformities such as contractures, genu valgum and genu varum.
  • Septic knee arthritis.
  • History of ligamentous injury or meniscal tear.
  • Cancer or any other malignancy or bone tumor.
  • Any history of previous lower limb arthroplasty or other knee surgery.
  • Comorbid like diabetes mellitus.
  • Inflammatory rheumatic disease (R.A).

Treatment and study plan

Myofascial Release

Other

It is a type of physical therapy often used to treat myofascial pain syndrome with pressure.

Neuromuscular Exercises

Other

Exercises commonly utilized in neuromuscular training programs to improve strength, balance , speed and agility. It will comprised of Warm-up, Lunges, Sideways exercises, Wall squats, Weight transfer exercise, Step up & down, Cool-down

Cold pack

Other

Application of cold pack around the patient's body, and covered with dry towel

Other names: Cold pack therapy

Primary outcomes

  1. Change in pain intensity on visual analogue scale after four weeks

    Time frame: Baseline and 4 weeks

    The Visual Analogue Scale is a unidimensional measure of pain intensity, used to record patients' pain progression, or compare pain severity between pains with similar conditions.. It is 0 to 10 cm scale. Patients rate their pain on that scale. Higher the score in centimeter, severe will be the pain experienced.

  2. Change in range of motion assessed with universal goniometer after four weeks

    Time frame: Baseline and 4 weeks

    The Goniometer is an instrument for the precise measurement of range of movement angles in degree , especially one used to measure the angles before and after range of motion.. Increase in the degree of angle suggests increase in range of movement.

Secondary outcomes

  1. Change in functional disability assessed with Knee injury and osteoarthritis outcome score after four weeks.

    Time frame: Baseline and 4 weeks

    The Knee Injury and Osteoarthritis Outcome Score (KOOS) is a knee-specific instrument, developed to assess the patients' opinion about their knee and associated problems regarding functional disability. In consists of total 100 scores. Increase in scores suggests decreased functional disability and decrease in scores suggests increased functional disability.

Sponsors and collaborators

Lead sponsor

Dow University of Health Sciences

Other

Registry information

Official study title

Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis: A Randomized Control Trial

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Sep 7, 2022
Registry last updated
Jan 9, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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