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OpenTrials
Completed

NCT Number: NCT07158632

Effects of Multiple Interventions on Under-Five Diarrhea

Diarrhea is the leading cause of death, especially in developed nations. Though there are effective interventions, diarrhea remains the leading cause of death among children in Ethiopia

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Key information

Conditions

Diarrheal Diseases Diarrhea Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

6 month–59 month

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Butajira Health Center

Butajīra, Ethiopia

About this study

Diarrheal disease is the major cause of child morbidity and mortality in low-income countries, including Ethiopia. Diarrhea is more common in areas with a lack of water sanitation and hygiene. Even though there are available effective interventions, diarrhea remains the major cause of child morbidity and mortality in Ethiopia. Therefore, the aim of this study is to give up-to-date information on multiple interventions that reduce diarrheal disease.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • a child age from 6 to 59 months Exclusion Criteria
  • child with persistent diarrhea, severely ill mother, households that receive treated water

Treatment and study plan

handwashing education

Behavioral

Arm A: This arm receive handwashing education using social and behavioral change communication

water chlorination

Behavioral

Arm B: This arm receives water chlorination intervention

Combined Intervention

Behavioral

Arm C: This arm receives combined handwashing and water chlorination intervention

Primary outcomes

  1. Incidence of diarrhea among under-five children

    Time frame: At baseline and to four-month follow-up

Secondary outcomes

  1. Adherence of interventions

    Time frame: Up to four-month follow-up

    percentage of soap availability near toilet and residual chlorine in drinking water

Sponsors and collaborators

Lead sponsor

Jimma University

Other

Registry information

Official study title

Effects of Maternal Handwashing Education and Household Water Chlorination on Diarrheal Disease Among Under-Five Children in Central Ethiopia Using RCT

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 8, 2025
Registry last updated
May 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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