Effects of Medical and Surgical Weight Loss on Metabolism

This study will follow ,morbidly obese subjects as they undertake weight loss before and after laparoscopic gastric banding, examining markers of glucose and lipid metabolism, adipokines and measures of body fat.

Completed

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Key information

Conditions

Type 2 Diabetes Body Weight Diabetes Mellitus Diabetes Mellitus, Type 2 Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

St Vincent's Hospital

Sydney, New South Wales, 2010, Australia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

morbidly obese subjects with type 2 diabetes or metabolic syndrome
age <70

Exclusion criteria

contra-indications to bariatric surgery

Treatment and study plan

Laparoscopic gastric banding

Procedure

standard surgical procedure

Primary outcomes

weight loss

Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Garvan Institute of Medical Research

Other

Registry information

Official study title

The Role of Adipocyte-derived Inflammatory Cytokines in the Pathogenesis of Diabetes, Dyslipidaemia, Atherosclerosis and Gastro-oesophageal Reflux Disease: the Effects of Medical and Surgical Weight Loss

Acronym: BOS

Important dates

Study start: 2007
Primary completion: 2012
Study completion: 2012
First posted: Jan 14, 2008
Registry last updated: Jun 7, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed