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NCT Number: NCT06751095

Effects Of Maitland's Mobilization At Mid Versus End Range In Knee Osteoarthritis Patients

Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most effective technique among all in decreasing pain sensitivity and increasing range of motion in knee OA.The aim of this study to compare effects of Maitland's mobilization at mid range versus end range on pain. range of motion and functional disability in patients with knee OA, providing useful insights for healthcare professionals to optimize treatment strategies and enhance outcomes in this context.

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Key information

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most effective technique among all in decreasing pain sensitivity and increasing range of motion in knee OA.The aim of this study to compare effects of Maitland's mobilization at mid range versus end range on pain. range of motion and functional disability in patients with knee OA, providing useful insights for healthcare professionals to optimize treatment strategies and enhance outcomes in this context.

This Randomized Clinical Trial will be conducted at DHQ Gujrat through consecutive sampling technique on 44 patients which will be allocated using simple random sampling through sealed opaque enveloped into (Group A and Group B).Maitland's mobilization at end range(Group A) incorporates the end range Maitland's mobilization,strengthening exercises, knee isometrics, transcutaneous electrical stimulation(TENS) and heating pad .

Maitland's mobilization in Mid range (Group B) will be treated with Mid range Maitland's mobilization, TENS,strengthening exercises,knee isometrics and heating pad.Outcomes, encompassing pain levels, range of motion(ROM), and functional disability will be evaluated through Visual analogue scale (VAS),Goniometer and WOMAC scale.The treatment plan spans 4 weeks, comprising 3 sessions per week. Data will be analyzed during SPSS software version 25. After assessing normality of data by Shapiro-wilk test, it will be decided either parametric or non-parametric test will be used within a group or between two groups. Data will be collected at baseline and after 4 weeks of follow up.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants with age between 40 to 60 years.
  • Participants of both genders will be included.
  • Patient with unilateral/bilateral symptomatic tibiofemoral knee OA.
  • Patient suffering from stiffness less than 30 minutes
  • Patients with radiologically diagnosed case of grade 2 knee OA according to the Kellgren and Lawrence scale
  • Patients with reported peak knee pain of >3 on visual analogue scale (VAS)

Exclusion criteria

  • Participants with acute inflammation of knee
  • Participants with severe degenerative lumbar spine disease e.g spondylolisthesis
  • Participants with systemic inflammatory arthritic or neurological conditions
  • Participants with intraarticular injection in the prior 3 months
  • Participants with unstable heart condition
  • Participants with received physical therapy of knee in last 3 months

Treatment and study plan

Maitland's Mobilization in End range

Other

End-range mobilization will be performed individually in flexion and extension end range of the tibiofemoral joint .(0-135 degree)

Maitland's mobilization in Mid range

Other

Mid range Maitland's mobilization will be performed in (approx. 50-70° knee flexion) of the tibiofemoral joint

Primary outcomes

  1. Numeric Pain Rating Scale

    Time frame: 4 Weeks

    The Numerical Pain Rating Scale (NPRS) is a commonly used self-report measure to assess the intensity of pain experienced by individuals. Participants rate their pain on a numerical scale, typically ranging from 0 (no pain) to 10 (worst possible pain).

Secondary outcomes

  1. WOMAC Osteoarthritis INDEX

    Time frame: 4 weeks

    The western Ontario and McMaster Universities Arthritis Index(WOMAC) is widely uses in the evaluation of Hip and Knee Osteoarthritis. It is a self administrated questionnaire consisting of 24 item divided into 3 sub-scales: Pain(5items) ,stiffness(2 items) and physical function (17 items)

  2. Universal Goniometer

    Time frame: 4 weeks

    It will measure range of motion of Knee

Study contacts

Contact information is provided by the study sponsor or research team.

Saba Rafique Dr., DPT, MS-OMPT

CONTACT

[email protected]

03034045433

Saba Rafique Dr., DPT,MS-OMPT

CONTACT

[email protected]

03034045433

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effects Of Maitland's Mobilization At Mid Versus End Range On Pain, Range Of Motion And Functional Disability In Patients With Knee Osteoarthritis.

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Dec 27, 2024
Registry last updated
Dec 27, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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