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OpenTrials
Completed

NCT Number: NCT01460225

Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation

This prospective study is designed to evaluate how lubiprostone may affect gastric motor and sensory function.

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Key information

Conditions

Chronic Idiopathic Constipation Constipation Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • chronic idiopathic constipation

Exclusion criteria

  • medications that slow gastrointestinal (GI) motility
  • prior surgery to the GI tract

Treatment and study plan

Lubiprostone

Drug

24 micrograms twice daily for 1 week

Primary outcomes

  1. Gastric Emptying

    Time frame: Day 1 and Day 7

    gastric emptying was measured before and after 7 days of treatment.at set times (2 and 4 hours post eating a radio-labeled meal)

Sponsors and collaborators

Lead sponsor

Dartmouth-Hitchcock Medical Center

Other

Collaborators

  • Takeda Pharmaceuticals North America, Inc.

Registry information

Official study title

Effects of Lubiprostone on Gastric Sensory and Motor Function in Patients With Chronic Idiopathic Constipation

Important dates

Study start
2007
Primary completion
2010
Study completion
2011
First posted
Oct 26, 2011
Registry last updated
Jul 13, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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