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Completed

NCT Number: NCT01784432

Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training

Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, low-level laser therapy has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations on global gene expression of muscle tissue influenced by exercise associated to low-level laser therapy.

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Key information

Conditions

Healthy

Age range

18 year–28 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Federal University of São Carlos

São Carlos, São Paulo, 13565-905, Brazil

About this study

This study assessed muscle performance in isokinetic dynamometry and leg press device; global gene expression of muscle tissue by microarray analysis

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy males aged between 18 and 28 years;
  • body mass index (BMI) equal to or less than 26 kg/m2;
  • moderated pattern of physical activity

Exclusion criteria

  • previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),
  • osseous or articular disorder in the lower limbs,
  • cardiovascular system disorders,
  • systemic disease, and
  • taking prescription medicines or using dietary supplements such as muscle mass builders

Treatment and study plan

Low-level laser therapy and training

Device

Other names: Laser, Laser therapy, Low-level laser therapy

Training

Other

Primary outcomes

  1. Global gene expression by microarray analysis

    Time frame: 12 weeks

Secondary outcomes

  1. Muscle performance in leg press device

    Time frame: 12 weeks

  2. Muscle performance in isokinetic dynamometer

    Time frame: 12 weeks

Other outcomes

  1. Immunohistochemical analysis

    Time frame: 12 weeks

    Immunohistochemical analysis to quantify morphology and cells of muscle tissue as satellite cells.

Sponsors and collaborators

Lead sponsor

Universidade Federal de Sao Carlos

Other

Collaborators

  • Centro de Pequisas de Ótica e Fotônica
  • Faculty of Medicine of Ribeirão Preto (FMRP-USP)
  • Fundação Hemocentro de Ribeirão Preto
  • Fundação de Amparo à Pesquisa do Estado de São Paulo

Registry information

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Feb 5, 2013
Registry last updated
Feb 5, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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