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OpenTrials
Completed

NCT Number: NCT02747719

Effects of Light and Exercise on Human Circadian Rhythms and Performance

Both light and exercise are effective countermeasures for space and ground-based crews for circadian phase resetting and alertness levels. The investigators propose to test the combined effects of these two countermeasures to determine whether adding exercise to light stimuli will further improve circadian phase resetting and alertness.

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Key information

Conditions

Circadian Rhythm

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy by history, physical exam, laboratory studies of blood and urine, and psychological screening
  • moderate-intensity exercise for at least 150 minutes per week

Exclusion criteria

  • color blind
  • no prescription medications, except hormonal birth control in females

Treatment and study plan

Light and exercise

Behavioral

Exposure to light and exercise

Primary outcomes

  1. Circadian Phase

    Time frame: 8 days

    Circadian Phase will be measured using the change in timing of the melatonin rhythm on different days of the protocol. Melatonin will be assayed in blood and/or saliva.

Secondary outcomes

  1. Subjective alertness

    Time frame: 8 days

    Subjective alertness will be measured using the change in values on standardized mood scales on different days of the protocol.

Sponsors and collaborators

Lead sponsor

Brigham and Women's Hospital

Other

Collaborators

  • NSBRI

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2018
First posted
Apr 22, 2016
Registry last updated
Jul 11, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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