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OpenTrials
Completed

NCT Number: NCT04629365

Effects of Ketogenic Diet in Body Builders

the study sought to investigate the influence of 8 weeks of a very low carbohydrate ketogenic diet on body composition, muscle strength, muscle area and blood parameters in competitive natural body builders.

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Key information

Conditions

Diet, Healthy Body Weight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Nutrition and Exercise Lab, DSB, University of Padova

Padova, 35131, Italy

About this study

nineteen natural body builders were randomly assigned to a ketogenic diet (KD) group or to a normal diet group (ND) with a traditional meal pattern. The two diets were isocaloric and included the same amount of protein per kg of body weight; but differed in the distribution of fats and carbohydrates; the latter were kept below 5% daily (less than 50g/day) in the KD group while represented 55% of the caloric intake in the WD group During the experimental period, training loads were similar in the two groups. Athletes were tested before and after 8 weeks of the intervention. Body composition , basal metabolism, muscle strength and blood parameters were measured.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • at least 5 years of training experiences
  • competing in recognized body building category

Exclusion criteria

  • adherence to special diets
  • use of nutritional supplements (except a daily multivitamin-mineral and/or protein supplement)
  • use of medications (steroids)
  • diabetes or metabolic diseases

Treatment and study plan

Ketogenic diet

Other

KD group consumed less than 50g/day of carbohydrates

Normal Diet

Other

ND group consumed 55% of the caloric intake from carbohydrates

Primary outcomes

  1. Fat Mass

    Time frame: 8 weeks

    fat mass measured through body impedence analyser

  2. Lean Body Mass

    Time frame: 8 weeks

    lean body mass mass measured through body impedence analyser

  3. Maximal muscle strength

    Time frame: 8 weeks

    muscle strength measured via 1-RM test

Secondary outcomes

  1. blood glucose

    Time frame: 8 weeks

    glucose as milligram per deciliter

  2. testosterone

    Time frame: 8 weeks

    Testosterone free as picogram per milliliter

  3. inflammatory cytokines

    Time frame: 8 weeks

    IL6, IL1β, TNFα measured as nanogram per deciliter

  4. resting metabolism

    Time frame: 8 weeks

    resting energy expenditure measured as Kcal / day

Sponsors and collaborators

Lead sponsor

University of Padova

Other

Registry information

Official study title

Effects of Two Months of Ketogenic Diet on Body Composition, Muscle Strength and Blood Parameters in Competitive Natural Body Builders

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Nov 16, 2020
Registry last updated
Nov 17, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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