Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).

Completed

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Key information

Conditions

Opiate Dependence Chemically-Induced Disorders Mental Disorders Narcotic-Related Disorders Opioid-Related Disorders Substance-Related Disorders

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Vilnius University Emergency Hospital

Vilnius, Lithuania

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed opiate dependence according to ICD 10 and/or DSM 4;
Duration of substance abuse more than 1 year
No or minor co-morbidities;
Grade I-II according to physical status classification system of American Society of Anesthesiologists.

Exclusion criteria

Current history of long acting opiate or poly-substance abuse;
Acute medical or surgical condition;
Pregnancy;
Breastfeeding.

Treatment and study plan

ketamine

Drug

Sponsors and collaborators

Lead sponsor

Vilnius University

Other

Registry information

Important dates

Study start: 2003
Study completion: 2006
First posted: Mar 9, 2006
Registry last updated: Nov 14, 2006

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed