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OpenTrials
Completed

NCT Number: NCT02083198

Effects of IV Chloride Content on Outcomes

This observational study evaluates the impact of high and low chloride containing IV fluids on administrative and clinical outcomes. The study uses a large electronic health dataset and examines patients receiving fluid replacement and resuscitation. The hypothesis is that high chloride solutions are associated with adverse outcomes as measured by administrative data and by clinical parameters.

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Key information

Conditions

SIRS Balanced Fluids Plasmalyte

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Baxter Healthcare

Deerfield, Illinois, 60015, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults meeting SIRS criteria receiving at least 500 mL of fluid replacement on day of SIRS.

Exclusion criteria

  • Receipt of starches or other colloids

Treatment and study plan

Primary outcomes

  1. Mortality

    Time frame: Hospitalization, Expected Length of inpatient stay is approximately 7 days

    Inpatient mortality. Expected Length of inpatient stay is approximately 7 days

Secondary outcomes

  1. Length of Stay

    Time frame: inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days

  2. Acute renal failure

    Time frame: inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days

  3. Infections

    Time frame: inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days

  4. dysrhythmias

    Time frame: inpatient hospitalization, Expected Length of inpatient stay is approximately 7 days

  5. Electrolyte disorders

    Time frame: inpatient hospitalizationExpected Length of inpatient stay is approximately 7 days

Other outcomes

  1. readmission

    Time frame: 30, 60 and 90 day

Sponsors and collaborators

Lead sponsor

Baxter Healthcare Corporation

Industry

Registry information

Official study title

A Comparison of High and Low Chloride Containing IV Fluid Solutions in Patients Undergoing Major Surgery and/or ICU Admission

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Mar 11, 2014
Registry last updated
Jun 21, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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