High Institute for Infertility Diagnosis and Assisted Reproductive Technology
Baghdad, Iraq
NCT Number: NCT06684951
a number of infertile women who were prepared for ICSI and immediately post ova pick up intrauterine flushing with human chorionic gonadotropin was done to study the effect of this drug on ICSI outcome and ultrasound parameter.
Looking for future studies?
Notify Me18 year–40 year
Female
Interventional
Phase 4
Baghdad, Iraq
Ninety infertile women included. Written informed consent was obtained before being included in the study. Three groups of patients according to type of intervention. Assessment of plasma hormone level was done for all. The quantification of serum TNF and IL-10 levels was conducted through the application of the enzyme-linked immunosorbent assay (ELISA) methodology at a privately-owned laboratory.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Endometrioses, whether clinically suspected or discovered during laparoscopy, are of interest.
-
observe hCG effect on endometrial receptivity
Time frame: at day of ova pickup a blood sample aspirated, and on day of embryo transfer about 3-5 days post ova pickup blood sample taken within ten minute before embryo transfer to asses serum level of TNF-alfa and IL-10 for all participent
All participants in the study had a blood sample taken on the day of ovum retrieval (within 10 minute after ova pickup) for the purpose of measuring the level of interleukin-10 and TNF-alfa in the blood, and a second sample was taken on the day of embryo transfer (ten minute before embryo transfer) to asses both marker,
Time frame: Within 10 minutes after ova pickup, ten minute before embryo transfer using ultrasound device
assessment of sub-endometrial blood flow indicis immediately within 10 minute post ova pickup and second exam within ten minute before embryo transfer day which is within 3-5 days of ova pickup there are no maximum or minimum value for the parameter to be measured and lower value is better these measure was performed by using ultrasound device
Time frame: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup
ultrasound parameter to asses endometrial receptivity by measuring sub-endometrial flow systole / diastole ratio
Time frame: within ten minute post ova pickup and ten minute prior to embryo transfer which is done within 3-5 days post ova pickup
ratio of serum level of TNA-alfa /IL-10 at time of ova pickup and at day of embryo transfer
Time frame: 14 days after embryo transfer beta-hCG titer performed to asses pregnancy
Number of patients who get pregnant after ICSI in each study group
Omayma Ismail Khalaf
Other
Study the Effects of Intrauterine Flushing With Low Dose Human Chorionic Gonadotropin on Ultrasound Parameter and Immunological Marker of Endometrial Receptivity of Infertile Female Undergoing ICSI Cycle
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04071574
Adnexal Diseases, Congenital Uterine Anomaly
Tripoli, North Lebanon, Lebanon
View Trial DetailsNCT01483612
Adnexal Diseases, Body Weight
Sherbrooke, Quebec, Canada
View Trial DetailsNCT04733235
Female Infertility, Female Urogenital Diseases
Antalya, Turkey (Türkiye)
View Trial DetailsNCT01620346
Female Infertility, Female Urogenital Diseases
São Paulo, Brazil
View Trial Details