Skip to main content
OpenTrials
Completed

NCT Number: NCT03128203

Effects of Intranasal Oxytocin on Striatal Functional Connectivity

To investigate whether 40 IU of intranasal oxytocin treatment can influence the resting-state functional connectivity in healthy males.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

School of Life Science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, 611731, China

About this study

In a double-blind, between-subject, placebo controlled design, investigators plan to investigate the effects of oxytocin treatment on resting-state functional connectivity.

Subject will receive either intranasal oxytocin or placebo administration and go through a seven-minute resting-state scan in MRI scanner to test whether oxytocin changes functional connectivity in the brain. Trait anxiety and mood questionnaires will be administered as control variables.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

  • with MRI Contraindications

Treatment and study plan

Oxytocin

Drug

Oxytocin, intranasally administrated

Placebos

Drug

Saline, intranasally administrated

Primary outcomes

  1. Striatal functional connectivity alterations after drug administration

    Time frame: 45 minutes after drug administration

    fMRI-based resting state connectivity of the striatum will be compared between the oxytocin and the placebo group

Sponsors and collaborators

Lead sponsor

University of Electronic Science and Technology of China

Other

Registry information

Official study title

Effects of Intranasal Oxytocin on Striatal Functional Connectivity in Healthy Males

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Apr 25, 2017
Registry last updated
Apr 25, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.