Skip to main content
OpenTrials
Completed

NCT Number: NCT01926431

Effects of Intense Exercise on Neural Responses to Food.

The primary aim of this study was to determine the effects of an acute bout of high intensity exercise on the brains response to viewing pictures of food using functional magnetic resonance imaging (fMRI).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Neural Responses Appetite Hormones Subjective Appetite Sensations

Age range

18 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Birmingham University Imaging Centre

Birmingham, Midlands, B15 2TT, United Kingdom

About this study

It is clear that intense exercise impacts on peripheral appetite regulation, however very little is known about the impact of high-intensity exercise on central appetite regulation. This study aimed to investigate the effects of high-intensity exercise on both central and peripheral responses to images of food. Functional magnetic resonance techniques were used to assess the brains response to images of high and low calorie foods, following a short bout of high-intensity exercise. Appetite hormone concentrations were also measured. It was hypothesized that, due to the known effects of high-intensity exercise on appetite regulatory hormones and subjective appetite ratings, the activation of reward-related brain regions to visual food cues would be modulated following intense physical activity.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy, non-smokers, free from cardiovascular disease and metabolic disease, no medication, participated in moderate/vigorous physical activity (>2 hours per week)

Exclusion criteria

  • Smokers, history of cardiovascular/metabolic disease, low physical activity levels, inability to participate in fMRI scanning sessions including contraindications to MRI

Treatment and study plan

Exercise

Other

Rest

Other

Primary outcomes

  1. Neural responses following exercise and rest

    Time frame: Ten minutes post-exercise/rest

    Volunteers completed an fMRI assessment following 60 minutes of intense exercise and 60 minutes of rest on two separate occasions.

Secondary outcomes

  1. Appetite hormones

    Time frame: Blood samples taken at baseline, following exercise/rest, prior to the fMRI assessment and immediately following the fMRI assessment

    Blood samples were taken using a cannula system for both trials. Concentrations of appetite regulating hormones were measured from plasma.

Sponsors and collaborators

Lead sponsor

University of Birmingham

Other

Registry information

Official study title

The Effects of High Intensity Exercise on Neural Responses to Images of Food

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Aug 21, 2013
Registry last updated
Aug 21, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.