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Completed

NCT Number: NCT01903772

Effects of Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease (COPD)

The additional effect of inspiratory muscle training as an adjunct to a general exercise training program in patients with COPD with inspiratory muscle weakness will be studied. The main hypothesis is that inspiratory muscle training combined with an exercise training program improves functional exercise capacity more than an exercise training program without the addition of an inspiratory muscle training program.

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Key information

Conditions

COPD Chronic Disease Disease Attributes Inspiratory Muscle Weakness Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

40 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Schön Klinik Berchtesgadener Land

Schönau am Königssee, Bavaria, 83483, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with COPD
  • Eligible to participate in an inpatient pulmonary rehabilitation program of 3 weeks
  • Pi,max <60 centimeters of water or <50% of the predicted normal value

Exclusion criteria

  • Major comorbidities preventing successful participation in an 8 week exercise training intervention
  • use of non-invasive ventilation

Treatment and study plan

Inspiratory Muscle Training

Other

Primary outcomes

  1. 6-Minute walking distance

    Time frame: change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program

Secondary outcomes

  1. exercise capacity (constant work rate test)

    Time frame: change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program

  2. maximal inspiratory pressure (PImax)

    Time frame: change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program

  3. inspiratory muscle endurance capacity

    Time frame: change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program

  4. dyspnea

    Time frame: change from the beginning at 3 weeks of a inpatient pulmonary rehabilitation program

    measured via Borg-scale at rest, during 6-minute walking distance, during constant work rate test at iso-time, during inspiratory muscle endurance capacity test

Sponsors and collaborators

Lead sponsor

Schön Klinik Berchtesgadener Land

Other

Collaborators

  • KU Leuven

Registry information

Acronym: IMTCO

Important dates

Study start
2013
Primary completion
2017
Study completion
2017
First posted
Jul 19, 2013
Registry last updated
Mar 3, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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