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OpenTrials
Completed

NCT Number: NCT01325038

Effects of Increased Muscle Mass on Resting Metabolic Rate

Healthy males are randomized to isometric exercise for three months with either extra protein or extra calories in the form of a fast food meal/day in order to study if increase in muscle mass increases resting metabolic rate and if this is affected by presumed increased caloric intake as compared with only proteins.

Body-composition was measured with Dual-Energy X-ray Absorbimetry (DEXA) and RMR was measured by registration of CO2 production and O2 consumption.

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Key information

Conditions

Healthy Subjects

Age range

18 year–45 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

University Hospital of Linkoping

Linköping, Sweden, 58185

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy males

Exclusion criteria

  • significant disease
  • inability to exercise

Treatment and study plan

Isometric exercise

Procedure

Isometric exercise several times/week for three months

Primary outcomes

  1. change in resting metabolic rate

    Time frame: 3 months

    measurement of resting metabolic rate at baseline and at the end of the three month trial period

Secondary outcomes

  1. change in muscle mass

    Time frame: 3 months

    measurement of muscle mass with DEXA at baseline and at the end of the three month trial period

Sponsors and collaborators

Lead sponsor

University Hospital, Linkoeping

Other

Registry information

Important dates

Study start
2008
Primary completion
2008
Study completion
2009
First posted
Mar 29, 2011
Registry last updated
Mar 29, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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