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OpenTrials
Completed

NCT Number: NCT04437758

Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes

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Key information

Conditions

Collagen Synthesis Behavior Motor Activity Rate of Force (RFD) Development

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

UC Davis Functional Molecular Biology Laboratory and Human Performance Laboratory

Davis, California, 95616, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy male athletes between 18-30 years of age
  • Currently participating in sport
  • <3 musculoskeletal injuries in the past year
  • No health or dietary restriction that would be affected by the supplementation protocol

Exclusion criteria

  • History of more than 3 musculoskeletal injuries within the past 12 months
  • Health, dietary restriction or diet that would be affected by the supplementation protocol
  • Willing to eat similar dietary pattern the day before baseline testing and each exercise testing/intervention day

Treatment and study plan

Collagen and Vitamin C powder mix nutritional intervention

Dietary Supplement

20 g collagen + 50 mg vitamin C daily, 60 min prior to exercise

Maltodextrin placebo powder

Other

20 g maltodextrin placebo daily, 60 min prior to exercise

Maximum power training exercise

Other

Explosive/power-based exercise training program 3 times/week at home consisting of drop jumps, box jumps, weighted jump squats loaded in a progressive manner weekly for 3 weeks. At baseline and at the end of each of the 3 weeks, measures of explosive performance are assessed in the lab (maximal isometric squat, counter-movement jump and squat jump)

Primary outcomes

  1. Maximal rate of force development (RFD) of isometric squat (MIS)

    Time frame: % change from baseline to week 1, week 2 and week 3

    Force (N) over time (msec) for the maximum slope of the first 20% of the movement

  2. Counter-movement jump (CMJ) rate of force development (RFD)

    Time frame: % change from baseline to week 1, week 2 and week 3

    CMJ jump performance N/s/kg

  3. Squat jump height rate of force development (RFD)

    Time frame: % change from baseline to week 1, week 2 and week 3

    Squat jump height performance RFD/kg

Other outcomes

  1. Maximum peak force of maximal isometric squat (MIS)

    Time frame: % change from baseline to week 1, week 2 and week 3

    Peak force (N)

  2. Counter-movement jump (CMJ) net eccentric impulse

    Time frame: % change from baseline to week 1, week 2 and week 3

    Jump performance max N/s/kg (Note: Eccentric is the drop down part of the CMJ)

  3. Counter-movement jump (CMJ) net concentric impulse

    Time frame: % change from baseline to week 1, week 2 and week 3

    Jump performance max N/s/kg (Note: Concentric is the movement upwards of the CMJ)

  4. Leg stiffness assessment

    Time frame: % change from baseline to week 1, week 2 and week 3

    Tendon stiffness mean per kg (N/m/kg)

Sponsors and collaborators

Lead sponsor

PepsiCo Global R&D

Industry

Registry information

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Jun 18, 2020
Registry last updated
Jun 18, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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