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Completed

NCT Number: NCT06935318

Effects of High Functional Resistance Training Program on Arterial Stiffness

Study examined the effects of CrossFit training on blood vessels. The results indicate long term CrossFit training does not harm blood vessel function.

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Key information

Conditions

Training Study

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Salisbury University

Salisbury, Maryland, 21801, United States

About this study

Arterial stiffness is a systemic loss of elastic properties that significantly augment cardiovascular disease risk in adults. Chronic aerobic and anaerobic exercise activity has consistently been shown to attenuate or not affect markers of arterial stiffness in adults with chronic disease and otherwise healthy adults. Chronic high functional resistance training's effect on vascular compliance is less understood. The study aimed to determine the impact of a chronic high functional resistance training program on pulse wave velocity and beta-stiffness index. Accordingly, participants (18-40 years old) were placed in a non-randomized fashion into high functional resistance training (HIB) group (n = 9; >6 months of CrossFit experience; 4 female) or control (CON) group (n = 8; < 6 months of exercise experience; 6 female). Participants in the HIB group trained at the same local facility 4 -5 days a week, utilizing the same training program. CON group refrained from exercise during the study period. Body composition, 1,000-meter rowing test, deadlift 1 repetition maximum (1 RM), hemodynamic assessments, and vascular compliance were assessed at baseline and follow-up.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • body weight stability with no more than ± 2.5 kg fluctuations in last six month

Exclusion criteria

  • hypertension
  • heart disease
  • cancer
  • diabetes
  • renal disease
  • hepatic disorders
  • history of tobacco use.

Treatment and study plan

Exercise

Other

The exercise group performed an 11-week high-functional resistance program in a group training format. They trained 3-4 days a week following nationally assigned workouts

Control

Other

Did not participate in exercise related activities for the duration of the study period.

Primary outcomes

  1. Pulse wave velocity

    Time frame: From enrollment to the end of treatment at 11 weeks

Sponsors and collaborators

Lead sponsor

Salisbury University

Other

Registry information

Official study title

Effects of an 11-Week High Functional Resistance Training Program on Indices of Arterial Stiffness

Important dates

Study start
2020
Primary completion
2023
Study completion
2024
First posted
Apr 20, 2025
Registry last updated
Apr 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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