Effects of High-Flow Nasal Cannula Therapy Assessed by Electrical Impedance Tomography

This study aimed to determine the effects of HFNC therapy on lung recruitment and lung strain change assessed by electrical impedance tomography (EIT)

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Key information

Conditions

High-flow Nasal Cannula Electrical Impedance Tomography

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences,

Beijing, Beijing Municipality, 100730, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion Criteria:
Patient who received a HENC therapy within 24 h after the extubation

Exclusion criteria

Aged <18 years
Pregnancy
Body mass index (BMI) over 50 kg/m2
ribcage malformation .any contraindication of using EIT monitoring (automatic implantable cardioverter defibrillator, chest skin injury, etc.).

Treatment and study plan

High-Flow Nasal Cannula (HFNC)

Other

24 patients who receiving HFNC within 24 hours after extubation were prospectively enrolled in this study. EIT was used to monitor regional lung ventilation distributions at baseline (conventional oxygen therapy) and three flow rate levels of HFNC therapy (20, 40 and 60 L/min).

Primary outcomes

lung regional ventilation distribution

Time frame: minute 80

lung regional ventilation distribution measured by EIT

Sponsors and collaborators

Lead sponsor

Peking Union Medical College Hospital

Other

Registry information

Official study title

Effects of High-Flow Nasal Cannula Therapy on Lung Recruitment and Lung Strain Change Assessed by Electrical Impedance Tomography

Important dates

Study start: 2018
Primary completion: 2019
Study completion: 2019
First posted: Jan 28, 2020
Registry last updated: Jan 28, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed