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OpenTrials
Completed

NCT Number: NCT03409497

Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults

Assess the impact of 100% grape juice with a meal on postprandial glycemic response and subsequent appetite, food intake and cognitive function.

Completed

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Key information

Conditions

Glycemic Response Appetitive Behavior Behavior Behavior, Animal

Age range

25 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Purdue University

West Lafayette, Indiana, 47909, United States

About this study

Investigators earlier studies and published literature suggest that the phenolic content and strong flavor intensity of 100% Concord grape juice hold potential beneficial effects on blood sugar levels. Investigators aim to better understand the consumption of 100% grape juice with a meal modifies appetite and glycemia acutely and over the day using a 24 hour glucose monitor.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI between 25.0-34.9 kg/m2
  • Willingness to eat all test foods
  • Low consumer of tea and coffee, willingness to refrain from both during the 48 hours prior to test days and on the test day
  • Fasting blood glucose below 6.1mmol/l via capillary finger-stick blood sample using a SureStep glucometer (Lifescan, Milpitas, CA)

Exclusion criteria

  • Taking medications known to affect glycemia, lipid metabolism or appetite
  • Body weight fluctuation of >5kg in the past 3 months
  • Taking vitamin or other supplements
  • Smokers
  • Acute or Chronic disease

Treatment and study plan

Concord Grape Juice

Other

Concord Grape Juice

Low flavonoid low essence beverage

Other

Low flavonoid low essence beverage

Low flavonoid beverage

Other

Low flavonoid beverage

Primary outcomes

  1. change in blood glucose over 24 hours

    Time frame: 24 hours

    samples taken every 5 minutes for 24 hours by a continuous glucose monitor

Secondary outcomes

  1. Appetite

    Time frame: 24 hours

    Questionnaire on hunger, fullness, desire to eat, prospective consumption, thirst taken hourly on same day as grape juice intervention

Sponsors and collaborators

Lead sponsor

Purdue University

Other

Collaborators

  • Welch's Food Corporation

Registry information

Important dates

Study start
2019
Primary completion
2019
Study completion
2020
First posted
Jan 24, 2018
Registry last updated
Nov 5, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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