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NCT Number: NCT07578779

Effects of Frenkels Exercises and Electrical Muscle Stimulation on Stroke Patients

To determine the combined effects of frenkel's exercises and electrical muscle stimulation on coordination, balance and proprioception in stroke patients.

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Key information

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Typically 50-65 years old.(14)
  • Both male and female are included
  • Patients with subacute ischemic stroke (hemiplegia).(15)
  • Ability to walk independently for at least 10minutes.(16)
  • Diagnosis of a first-time stroke or without sequel of a previous stroke(15)
  • MOCA score>26 to confirm adequate cognitive function.
  • Brunnstrom exercise recovery stages of 3-4 or higher(17)
  • Voluntarily provided informed consent prior to participating

Exclusion criteria

  • Patients with severe cognitive impairment or dementia.(16)
  • Patients with unstable medical conditions, such as uncontrolled hypertension or cardiac disease.
  • Patients with recent surgery or injury that may affect participation in the study.
  • Patients with contraindications to electrical muscle stimulation (EMS), such as unstable cardiopulmonary medical conditions pacemakers or metal implants

Treatment and study plan

Frenkels exercise with EMS

Other

Group A will include 19 participants. Participant will receive EMS for 10 minutes and Frenkels exercise for 20 minutes for 3 days per week for 8 weeks In Week 1-2 Investigator will apply 50Hz EMS pulse duration of 150 μs, intermittent with 5s of EMS stimulation to perform the movement and 10s of rest stimulation for adaptation while focusing lower limb exercises in according to frenkles exercises for 20 min in lying position Week 3-4: 60 Hz EMS stimulation applied pulse duration of 200 μs, intermittent with 5 s of EMS stimulation to perform the movement and 10 s of rest with frenkles exercises in sitting position Week 5-6 Frequency of 70 Hz pulse duration of 250 μs, intermittent with 5 s of EMS stimulation to perform the movement and 10 s of rest EMS stimulation will be applied with frenkles exercises in standing position Week 7-8: In progression, Frequency of 85 Hz and pulse duration of 300 μs, intermittent with 5 s of EMS stimulation to perform the movement and 10 s of rest

Conservative treatment

Other

Group B will also include 19 participants. Each participant will receive routine therapy for 30 minutes. It could be hot pack, IR with routine exercises for 3 days per week for 8 weeks.

Weeks 1-2: Initial Phase

  • Breathing exercises
  • Range of motion exercises
  • Seated exercises Weeks 3-4: Strengthening Phase Resistance band exercises: Upper and lower limb strengthening

b) Weight-bearing exercises c) Gait training: Walking with support d) Balance exercises: Weeks 5-6 Functional Phase

  • Functional activities: Reaching, scooting, transferring
  • Gait training: Walking without support, navigating obstacles
  • Balance exercises: Dynamic balance, reaction training
  • Strengthening exercises:

Weeks 7-8: Advanced Phase

  • Advanced gait training: Stair climbing, curbs, uneven surfaces
  • Complex functional activities: Cooking, dressing, household chores

Primary outcomes

  1. The Berg Balance Scale (BBS)

    Time frame: Baseline and 8th week

    It's a 14-item performance-based measure, meaning it assesses how well a person can perform specific tasks related to balance. Each item is scored on a 5-point scale (0-4), with higher scores indicating better balance, and a total score range of 0-56.

  2. The Nottingham Sensory Assessment (NSA)

    Time frame: baseline and 8th week

    NSA is used to evaluate sensory impairments, particularly in individuals who have experienced stroke.

    scores ranging from 0 (extreme difficulty/unable to perform) to 4 (no difficulty) for each item.

  3. The Lower Extremity Motor Coordination Test (LEMOCOT)

    Time frame: Baseline and 8th Week

    (LEMOCOT) scoring scale involves assessing an individual's ability to perform specific lower extremity movements, with scores ranging from 0 (extreme difficulty/unable to perform) to 4 (no difficulty) for each item. The total score is obtained by summing the scores of all items, with a higher score indicating better motor coordination.

Study contacts

Contact information is provided by the study sponsor or research team.

Imran Amjad, Phd

CONTACT

[email protected]

03324390215

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Combined Effects of Frenkels Exercises and Electrical Muscle Stimulation on Balance, Coordination and Proprioception in Stroke Patients

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 11, 2026
Registry last updated
Jun 10, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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