Skip to main content
OpenTrials
Completed

NCT Number: NCT02666586

Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control

To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).

Completed

Looking for future studies?

Notify Me

Key information

Age range

20 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Richardson Centre for Functional Foods and Nutraceuticals

Winnipeg, Manitoba, R3T 2N2, Canada

About this study

The overall objective is to describe the effect and mechanisms of action of faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years). The specific objectives are to test the acute effects of different faba bean ingredient smoothie on: 1) post-prandial blood glucose, appetite, satiety hormone and insulin for 200 minutes, and 2) food intake 120 minutes following consumption of the faba bean smoothie. Two short-term acute studies will be conducted to meet these objectives. Both acute studies will follow a randomized, double blinded, balanced, repeated measures design and the same protocol; except one will have an ad libitum pizza meal (study 1), while the other will have a fixed pizza meal (study 2) at 120 minutes. Half the participants will have blood drawn by IV and the other half will be finger prick.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • healthy
  • non-smoking males
  • aged 20-30 years (min/max age)
  • a body mass index between 20 and 25 kg/m2 (the range generally accepted as ideal/healthy by Health and Welfare Canada)

Exclusion criteria

  • individuals diagnosed with diabetes
  • those on medication
  • breakfast skippers
  • on an energy restricted diet
  • this study excludes females because appetite and blood glucose during the female menstruation cycle changes due to fluctuations in hormones

Treatment and study plan

Faba bean powder smoothie

Other

Breakfast smoothie with 32 g whole faba bean powder (300g).

Faba bean protein concentrate smoothie

Other

Breakfast smoothie with 32 g faba bean protein concentrate.

Faba bean starch smoothie

Other

Breakfast smoothie with 33 g faba bean starch.

Faba bean protein isolate smoothie

Other

Breakfast smoothie with 32 g faba bean protein isolate.

Non-pulse smoothie smoothie

Other

Control smoothie with 32 g corn maltodextrin without added faba bean fractions.

Primary outcomes

  1. blood glucose

    Time frame: 0-200 minutes

    measured by finger prick blood samples by glucose meters

Secondary outcomes

  1. appetite

    Time frame: 0-200 minutes

    measured by VAS questionnaire

  2. satiety hormones

    Time frame: 0- 200mins

    measured by enzyme-linked immunosorbent assay (ELISA)

  3. insulin

    Time frame: 0-200mins

    measured by ELISA

  4. food intake

    Time frame: 120 minutes following consumption of the faba bean smoothie

    energy intake at ad-libitum pizza meal

  5. physical comfort

    Time frame: 0-200 minutes

    measured by VAS questionnaire

  6. energy/fatigue

    Time frame: 0-200 minutes

    measured by VAS questionaire

Sponsors and collaborators

Lead sponsor

University of Manitoba

Other

Registry information

Important dates

Study start
2016
Primary completion
2017
Study completion
2017
First posted
Jan 28, 2016
Registry last updated
Jan 23, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.