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NCT Number: NCT07335068

Effects of Exercise Snacking on Physical Fitness, Cognition, and Pain in Institutionalized Older Adults

This study aims to compare the effects of two different exercise approaches on health and well-being in older adults living in residential care facilities. One approach, called "exercise snacking," consists of short and frequent bouts of physical activity spread throughout the day, while the other involves longer, structured exercise sessions performed a few times per week.

Approximately 75 adults aged 65 years and older will be randomly assigned to one of the two exercise programs and will participate for 12 weeks. The study will examine whether exercise snacking is as effective as conventional exercise in improving physical fitness, cognitive function, chronic pain intensity, quality of life, and symptoms of anxiety and depression.

The researchers hypothesize that short, intermittent exercise sessions may provide similar or greater health benefits compared to traditional exercise programs and may represent a practical and accessible strategy to promote physical activity in older adults living in institutional settings.

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This study is active but is not currently recruiting participants.

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Key information

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Associação Casapiana de Solidariedade

Lisbon, 1500-661, Portugal

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 65 years
  • Residence in Associação Casapiana de Solidariedade

Exclusion criteria

  • Severe cognitive impairment (MMSE 0-10)
  • Unstable medical conditions (e.g., decompensated heart failure)
  • Refusal of consent
  • Total inability to walk/move.

Treatment and study plan

Exercise Snacks

Behavioral

Exercise snacks, defined as short bouts of gentle intermittent exercise performed twice a day

Conventional Exercise

Behavioral

Conventional exercise consists of longer continuous practice of structured physical activity.

Primary outcomes

  1. Physical Fitness Assessed by the Short Physical Performance Battery (SPPB)

    Time frame: Baseline and 3 months

    The Short Physical Performance Battery (SPPB) is a test of lower extremity functioning that combines scores from usual gait speed, standing balance, and chair stand tests. Scores range from 0 to 12, with higher scores indicating better physical functioning.

Secondary outcomes

  1. Anxiety and depression assessed by Hospital Anxiety and Depression Scale (HADS) subscale scores

    Time frame: From baseline to 3 months

    HADS consists of two subscales, one measuring anxiety, with seven items, and one measuring depression, with seven items, which are scored separately. Each item was answered by the participant on a 4-point (0-3) response category so the possible scores ranged from 0 to 21 for anxiety and 0 to 21 for depression. The HADS manual indicates that a score between 0 and 7 is ''normal'', between 8 and 10 ''mild'', between 11 and 14 ''moderate'' and between 15 and 21 ''severe''.

  2. Nordic Musculoskeletal Questionnaire (NMQ)

    Time frame: From baseline to 3 months

    Pain will be assessed using the Nordic Musculoskeletal Questionnaire. Participants will report as yes/no the presence of chronic pain (pain that persists or recurs more than three months) in nine body regions (neck, shoulders, elbows, wrists/hands, upper back, lower back, hips/thighs, knees, and ankles/feet). Symptom intensity in the last 7 days will be rated on a numeric scale from 0 to 10, where 0 indicates no pain and 10 indicates the worst possible pain.

  3. The 12-Item Short-Form Health Survey (SF-12)

    Time frame: From baseline to 3 months

    The SF-12 includes 12 items covering eight health domains (physical functioning, role physical, bodily pain, general health, vitality, social functioning, role emotional, and mental health). Responses will be scored using standard algorithms to generate two summary measures: the Physical Component Summary (PCS) and the Mental Component Summary (MCS). Scores will range from 0 to 100, with higher scores indicating better health-related quality of life. Outcomes will be reported as mean PCS and MCS scores.

  4. Mini-Mental State Examination (MMSE)

    Time frame: From baseline to 3 months

    Cognitive function will be assessed using the MMSE, a standardized interviewer-administered screening tool. The MMSE will evaluate orientation, attention, memory, language, and visuospatial abilities. Total scores will range from 0 to 30, with higher scores indicating better cognitive function. Cognitive impairment will be defined according to education-adjusted cut-off scores, as follows: illiterate participants ≤15 points; participants with 1 to 11 years of education ≤22 points; and participants with more than 11 years of education ≤27 points.

Sponsors and collaborators

Lead sponsor

Ivan Patrício

Other

Collaborators

  • Associação Casapiana de Solidariedade
  • CIDEFES - Universidade Lusofona

Registry information

Official study title

The Effects of Exercise Snacking on Physical Fitness, Cognitive Function, and Chronic Pain in Institutionalized Older Adults: A Randomized Controlled Trial

Acronym: EXSNAKS

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 12, 2026
Registry last updated
Mar 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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