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Completed

NCT Number: NCT01542775

Effects of Exercise on sRAGE Levels and Cardiometabolic Risk Factors

The purpose of this study is to examine the effects of exercise on diverse cardiometabolic risk factors and indicators of atherosclerosis in patients with type 2 diabetes mellitus (T2DM).

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Key information

Conditions

Type 2 Diabetes Diabetes Mellitus Diabetes Mellitus, Type 2 Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Eulji University School of Medicine

Seoul, 139-711, South Korea

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • type 2 diabetes
  • stable body weight
  • sedentary lifestyle

Exclusion criteria

  • smoked cigarettes
  • cardiovascular disease
  • chronic kidney
  • chronic liver disease
  • pregnant or breastfeeding
  • any other major illness

Treatment and study plan

Aerobic Exercise Group

Behavioral

12 weeks Aerobic exercise

Control Group

Behavioral

maintaining usual activities

Primary outcomes

  1. change from baseline in soluble receptor for advanced glycation endproducts (sRAGE) after 12 weeks of aerobic exercise

    Time frame: 12 weeks

Secondary outcomes

  1. anthropometric parameters

    Time frame: 12 weeks

    body weight, waist circumference, body fat percentage, visceral fat area

  2. biochemical parameters

    Time frame: 12 weeks

    HbA1c, apolipoprotein B, free fatty acid

  3. energy expenditure

    Time frame: 12 weeks

    activity energy expenditure, total energy expenditure

Sponsors and collaborators

Lead sponsor

Korea University

Other

Registry information

Important dates

Study start
2010
Primary completion
2011
First posted
Mar 2, 2012
Registry last updated
Mar 2, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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