St Mary's Hospital, The Catholic University of Korea
Seoul, 150-713, South Korea
NCT Number: NCT00606619
The aim of this study is to determine whether early oral feeding after curative resection for gastric cancer would be tolerable and give an effect on the recovery.
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Notify Me20 year–75 year
All sexes
Interventional
Phase 3
Seoul, 150-713, South Korea
Most patients who undergo gastric resection for gastric cancer have maintained going on a fast of over three days after operation. Surgeons have believed that early oral feeding might worsen patients' condition by prolonged postoperative ileus. Therefore, patients received nothing by oral route until resolution of the ileus. However, the current trend toward minimal operative injury and early discharge from hospital. In addition, development of operative technique and instrument make the operation time to be short and the patients to be fast recovery, and thus it is possible to feed early in less than two days after operation. The aim of this study is to determine whether early oral feeding after curative resection for gastric cancer would be tolerable and give an effect on the recovery.
We collect fifty-eight patients for this study and divide into two groups using randomization method. In the early feeding group, patients will receive the liquid diet two day after operation followed by soft diet postoperative three day. Meanwhile, the patients who categorized into control group will start the liquid diet postoperative four day followed by soft diet postoperative six day. We evaluate the morbidity or mortality rate and laboratory findings. Of course, it is supposed to be same in amount of fluid and calories between two groups.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Patients who underwent gastrectomy for adenocarcinoma of stomach with following criteria:
Exclusion criteria
Procedure of Conventional feeding group: Patients are supplied water on day 3 after operation, liquid diet on day 4 and 5 and soft diet on 6 day.
Procedure of Early oral feeding group: Patients are supplied water on day 1 after operation, liquid diet on day 2 and soft diet on day 3 day.
Time frame: within 30 days after operation
We measure the length of hospital stay after operation
Time frame: within 30 days after operation
We measure the days of flatus within 30 days after operation
Time frame: 1,3,5 and 7 day after operation
Time frame: before operation and 1,3,5,7 day after operation
Time frame: within 30 days after admission
We measure total cost from admission to discharge after operation
Time frame: 1,2 and 3 month after operation
Time frame: before operation and 1,3,5,7 day after operation
Time frame: within 30 days after operation
We observe the occurrence of morbidity after operation
The Catholic University of Korea
Other
Phase III Clinical Trial for Effect Early Oral Feeding on Recovery After Resection of Gastric Cancer
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