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Completed

NCT Number: NCT06070480

Effects of Different Types of Anaesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery

The aim of this study was to investigate the effects of anaesthesia methods on intraocular pressure during lumbar disc surgery performed in the prone position.

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Key information

Conditions

Anesthesia Disk Herniated Lumbar Intraocular Pressure

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Elvan Tekir Yılmaz

Giresun, Gi̇resun, 28100, Turkey (Türkiye)

About this study

The study included 75 patients with lumbar disc herniation between the ages of 18-75, with the American Society of Anesthesiologists (ASA) 1-2. The patients were randomly divided into 3 groups: propofol, desflurane, spinal. Intraocular pressure (IOP) was measured at 5 time points throughout surgery, including baseline (T1), 10 minutes after anesthesia (T2), 10 minutes after prone positioning (T3: early prone), 30 minutes after prone positioning (T4: late prone), and 10 minutes after returning to the supine position (T5). Hemodynamic parameters were measured at these time points. Hemoglobin and hematocrit values were measured preoperatively and on the first postoperative day.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA 1-2 according to the American Society of Anesthesiologists (ASA) Classification.

Exclusion criteria

  • Who did not sign the informed consent form,
  • patients who required emergency surgery,
  • eye surgery recipients,
  • subjects with acute or chronic eye diseases other than refractive errors,
  • individuals detected to have elevated IOP in preoperative measurements

Treatment and study plan

Spinal Anesthesia Group

Other

Effect of spinal anesthesia on intraocular pressure

Desflurane Group

Other

Effect of general anesthesia with desflurane on intraocular pressure

Propofol group

Other

Effect of general anesthesia with propofol on intraocular pressure

Primary outcomes

  1. intraocular pressure

    Time frame: Time 1:baseline supine , Time 2: 10. minute supine, Time 3: 20. minute prone , Time 4: 30. minute prone,Time 5: 10. minute after returning to the supine

    Intraocular pressure was measured a total of 5 times at set time points throughout the procedures.

Secondary outcomes

  1. Mean Arterial Pressure

    Time frame: Time 1:baseline supine , Time 2: 10. minute supine, Time 3: 20. minute prone , Time 4: 30. minute prone,Time 5: 10. minute after returning to the supine

    Mean Arterial Pressure was measured a total of 5 times at set time points throughout the procedures.

  2. Heart Rate

    Time frame: Time 1:baseline supine , Time 2: 10. minute supine, Time 3: 20. minute prone , Time 4: 30. minute prone,Time 5: 10. minute after returning to the supine

    Heart Rate was measured a total of 5 times at set time points throughout the procedures.

  3. End Tidal Carbon Dioxide (CO2)

    Time frame: Time 1:baseline supine , Time 2: 10. minute supine, Time 3: 20. minute prone , Time 4: 30. minute prone,Time 5: 10. minute after returning to the supine

    End Tidal CO2 was measured a total of 5 times at set time points throughout the procedures.

Sponsors and collaborators

Lead sponsor

Giresun University

Other

Registry information

Official study title

Effects of Propofol, Desflurane and Spinal Anesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery: A Randomized Controlled Study

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Oct 6, 2023
Registry last updated
Oct 6, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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