Effects of Different Occlusion Angles of Disposable Tracheal Blocker on Right One-lung Ventilation

This trial is a practical, multi-center, prospective, parallel grouping, randomized controlled,two-arm clinical study comparing the different occlusion angles of disposable tracheal blocker on right one-lung ventilation. It is planned to enroll 96 subjects requiring right-sided One-Lung ventilation, aged 18-65 years, at three centers. Patients will be randomly assigned to the tip opening angle to the right (Group R), or he tip opening angle to the left (Group L). The primary outcome is the satisfaction with intraoperative collapse of the right lung. The secondary outcome is the one-time success rate of occuder implantation

Inclusion criteria

• Age ranged from 18 to 65 years old;
• American Society of Anesthesiologists (ASA) grade I-III;
• No history of drug allergy or abnormal anesthesia;
• Patients undergoing right thoracoscopic surgery;
• The preoperative oxygen saturation was not less than 94%.

Exclusion criteria

• Patients with a history of acute lung injury or ARDS within 3 months;
• Cardiac function class IV (New York Heart Association classification);
• Chronic renal failure (renal cell filtration rate <30ml min-11.73m-2), severe liver disease;
• Patients with blurred consciousness and cognitive dysfunction;
• Patients with severe coagulation dysfunction;
• Without preoperative oxygen inhalation, blood oxygen <94%, severe pulmonary dysfunction;
• Patients with endotracheal tube admitted to ICU after operation;
• Body mass index (BMI) >30;
• Patients who had had lung surgery；
• Inability to complete the study;