Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels

To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level non-invasively and continuous measurement and to determine the contribution of smoking to the intraoperative carbon monoxide accumulation.

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Key information

Conditions

Fresh Flow Behavior Carboxyhemoglobinemia Smoking

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Zonguldak Bülent Ecevit University Medicine Faculty

Zonguldak, Kozlu, 67600, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ASA I-II
Undergo 2-4 hours of elective surgery

Exclusion criteria

Cardiovascular disease
diabetes mellitus
kidney, liver failure
chronic obstructive pulmonary disease
patients with opioid sensitivity
morbidly obese
personal or family history of malignant hyperthermia
history of prolonged recovery from anesthesia
alcohol addicted
pregnant and breastfeeding women patients allergic to study drugs

Treatment and study plan

radical-7 pulse co-oximeter

Device

COHb measurement monitoring from finger pulp with a non-invasive measurement device called Masimo Radical-7 Pulse co-oximeter (Masimo Corporation, Irvine, USA)

Primary outcomes

effects of different fresh gas flows on carboxyhemoglobin levels

Time frame: during surgery

To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level by non-invasive and continuous measurement.

Secondary outcomes

effects of smoking on carbon monoxide accumulation.

Time frame: during surgery

to determine the contribution of smoking to intraoperative carbon monoxide accumulation.

Sponsors and collaborators

Lead sponsor

Zonguldak Bulent Ecevit University

Other

Registry information

Official study title

Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels: Noninvasive Carbon Monoxide Monitoring

Important dates

Study start: 2016
Primary completion: 2018
Study completion: 2019
First posted: Apr 5, 2021
Registry last updated: May 3, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed