Effects of Dietary Pork and Egg on Appetite, Meal-patterning, and Weight Loss in Men

The purpose of this study is to identify how adult men respond to a weight loss diet that includes pork and eggs and increasing the number of meals consumed throughout the day. This is a 13-week study (12-weeks of weight loss and 1-week of baseline measurement).

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Key information

Conditions

Weight Loss Body Weight Body Weight Changes Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

21 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Purdue University

West Lafayette, Indiana, 47907, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age range: 21 years and older
Body mass index between 25.0-39.9 kg/m2
Weight stable (< 4.5 kg (~10 lbs) weight gain or loss within last 6 months)
Body fat >25% (assessed by skinfold and plethysmography (if needed))
Non-smoking (within the last 6 months)
Constant habitual activity patterns (within last 3 months)
Clinically normal blood profiles (specifically, normal liver and kidney function; fasting blood glucose <110 mg/dl)
Not taking medications known to influence appetite or metabolism
Non-diabetic

Exclusion criteria

Age: <21 years
Body mass index: outside of the 25.0-39.9 kg/m2 range
Gained or lost > 4.5 kg (10 lbs) within the last 6 months
Body fat <25% as assessed by plethysmography
Smoker (currently or within the last 6 months)
Intermittently been involved in a diet and/or exercise program within the last 3 months
Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
Clinically diagnosed as diabetic
Allergies to eggs
Lactose intolerance
Clinically diagnosed with diverticulosis
Clinically diagnosed with diverticulitis

Treatment and study plan

Energy restriction

Other

Energy restricted diet of 750 kcal less than subjects requirement with a high protein diet.

Primary outcomes

The primary aim is to examine the effects of increased protein intake on appetite, selected appetite hormones (insulin, leptin, ghrelin), whole body energy expenditure, and body composition (fat mass and fat-free mass) changes.

Time frame: 12 week

Secondary outcomes

The secondary aim of this study is to evaluate the effects of meal frequency on appetite by asking the men to frequently rate their appetite on days that they purposefully eat 3 vs. 6 times/day.

Time frame: 12 week

Sponsors and collaborators

Lead sponsor

Purdue University

Other

Registry information

Important dates

Study start: 2007
Primary completion: 2009
Study completion: 2011
First posted: Dec 22, 2008
Registry last updated: Jan 17, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed