Effects of Dietary Nitrate on Age-related Vascular Function

Purpose of the study is to characterize the chronic effect of dietary nitrate on vascular function in healthy volunteers with particular emphasis on age-related alterations.

Completed

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Key information

Conditions

Endothelial Dysfunction

Age range

55 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Heinrich-Heine-University

Düsseldorf, North Rhine-Westphalia, 40225, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

>55 Years Healthy

Exclusion criteria

known cardiovascular disease

Treatment and study plan

Nitrate

Dietary Supplement

Placebo

Dietary Supplement

Primary outcomes

Endothelial function measured by flow-mediated dilation (FMD)

Time frame: 30 days

The effect of dietary nitrate on endothelial function as measured by flow-mediated dilation (FMD) after forearm ischemia and reperfusion.

Sponsors and collaborators

Lead sponsor

Heinrich-Heine University, Duesseldorf

Other

Registry information

Official study title

Effects of Dietary Nitrate Supplementation on Age-related Vascular Dysfunction

Important dates

Study start: 2012
Primary completion: 2013
Study completion: 2013
First posted: Nov 20, 2012
Registry last updated: Dec 9, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed