Effects of Dexamethasone on Common Bile Duct Cannulation Time

The main aim of this clinical trial is to evaluate the effects of dexamethasone on common bile duct cannulation time during endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary pathologies. The study will also study the effects of dexamethasone on total procedure time and total fluoroscopy time during ERCP.

Participants will be divided into two groups, treatment group and placebo group. Patients in treatment group will receive dexamethasone and those in placebo group will be given normal saline before undergoing ERCP. The results in both groups will be compared to determine the effects of dexamethasone.

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Key information

Conditions

Common Bile Duct Diseases Bile Duct Diseases Bile Duct Neoplasms Biliary Tract Diseases Biliary Tract Neoplasms Calculi Cholecystolithiasis Cholelithiasis Common Bile Duct Calculi Common Bile Duct Dilatation Common Bile Duct Neoplasms Common Bile Duct Stricture Digestive System Diseases Digestive System Neoplasms Gallbladder Diseases Gallstones Neoplasms Neoplasms by Site Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Gujranwala Medical College Hospital

Gujranwala, Punjab Province, 52070, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age: 18 years or above
Both genders, male and female patients

Exclusion criteria

Age younger than 18 years or below
Pregnant females
Pre existing stent in CBD or pancreatic duct
Previous history of ERCP
Patients with billroth II surgery
Anatomical abnormalities
Lack of competence in patients
Roux en Y gastric bypass
Patients with contra indications for steroids like DM

Treatment and study plan

Dexamethasone 4mg

Drug

An injection of 4mg of dexamethasone will be given to patients approximately 2 to 4 hours prior to the procedure of ERCP.

Other names: steroids

Primary outcomes

Shortening of CBD cannulation time

Time frame: CBD cannulation time will be calculated from the start of the procedure (0 minutes) till complete CBD cannulation has been achieved through catheter and confirmed by fluoroscopy or procedure abandoned if unsuccessful cannulation by 30 minutes.

To determine the effects of dexamethasone on shortening of CBD cannulation time

Sponsors and collaborators

Lead sponsor

Gujranwala medical college District Headquarters Hospital, Gujranwala

Other

Registry information

Official study title

Can Deep Common Bile Duct Cannulation Time During Endoscopic Retrograde Cholangiopancreatography Be Shortened by Dexamethasone

Important dates

Study start: 2023
Primary completion: 2024
Study completion: 2024
First posted: Jul 14, 2023
Registry last updated: Mar 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed