Skip to main content
OpenTrials
Completed

NCT Number: NCT04175353

Effects of Dairy- and Berry-based Snacks on Postprandial Glucose Metabolism in Older People

Malnutrition or its risk is common among older people. To maintain adequate nutrition, increased meal frequency is important. In addition to main meals, regular consumption of nutrient- and energy-dense snacks is recommended. The study examines the post-meal responses to dairy- and berry-based snacks tailored for older people. The plasma concentrations of glucose, insulin and free fatty acids are measured during three hours after snack consumption. In addition, subjective satiety responses and heart rate variability are recorded.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Postprandial Hyperglycemia Glucose Metabolism Disorders Hyperglycemia Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Eastern Finland

Kuopio, Finland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Home-dwelling

Exclusion criteria

  • Smoking
  • Type 1 diabetes
  • Type 2 diabetes treated with oral medications or insulin
  • Cognitive impairment
  • Antibiotic medication within the past 3 months
  • Blood donation within the past month

Treatment and study plan

Dairy snack

Dietary Supplement

The effects of dairy snack are compared with orange juice.

Berry snack

Dietary Supplement

The effects of two berry snacks are compared with berry soup.

Primary outcomes

  1. Change in postprandial glucose

    Time frame: 3 hrs

    Changes in plasma glucose concentration within 3 hrs after meal

  2. Change in postprandial insulin

    Time frame: 3 hrs

    Changes in plasma insulin concentration within 3 hrs after meal

Secondary outcomes

  1. Change in postprandial free fatty acids

    Time frame: 3 hrs

    Changes in plasma free fatty acid concentration within 3 hrs after meal

  2. Change in postprandial satiety scores assessed by using visual analogy scales

    Time frame: 3 hrs

    Visual analogue scales (VAS) are used to assess satiety and other related subjective sensations (fullness, hunger, desire to eat, alertness) within 3 hrs after meal. Each VAS consists of a 100-mm horizontal line anchored with verbal descriptions at each end expressing the weakest (0 mm) or strongest (100 mm) statement of sensation. Results are scores between 0 and 100.

  3. Heart rate variability

    Time frame: 3 hrs

    Electrocardiography monitoring for assessment of several variables of heart rate variability

Sponsors and collaborators

Lead sponsor

University of Eastern Finland

Other

Registry information

Official study title

Tailored Food Solutions for Improving Nutrition and Well-being in Older People: Effects on Postprandial Responses

Acronym: MAVIRE2

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Nov 25, 2019
Registry last updated
Nov 25, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.